当前位置: 首页 > 文章 > 正交试验法优化叶黄素软胶囊制备处方 石河子大学学报(自然科学版) 2011,29 (2) 215-217
Position: Home > Articles > Optimization of Lutein Soft Capsule Preparation by Orthogonal Experiment Journal of Shihezi University(Natural Science) 2011,29 (2) 215-217

正交试验法优化叶黄素软胶囊制备处方

作  者:
尹俊涛;鲁萍;闫丽丽;王新春
单  位:
石河子大学药学院;石河子开发区神内食品有限公司
关键词:
叶黄素;软胶囊;正交设计;内容物
摘  要:
以药用大豆油为分散介质,蜂蜡为助悬剂,大豆磷脂为润湿剂,以沉降比和再分散性为指标,正交设计优选叶黄素软胶囊内容物的制备处方。结果表明,叶黄素软胶囊内容物的最佳配比为叶黄素-玉米黄素-药用大豆油-蜂蜡-大豆磷脂(14.4∶0.6∶80∶1∶4),制备得到的软胶囊内容物均匀、稳定、流动性好。
译  名:
Optimization of Lutein Soft Capsule Preparation by Orthogonal Experiment
作  者:
YIN Juntao1,LU Ping2,YAN Lili2,WANG Xinchun2(1 Shihezi Development Zone Jinnai Food Co.Ltd.,Shihezi 832000,China;2 School of Pharmacy,Shihezi University,Shihezi 832000,China)
关键词:
lutein;soft capsule;orthogonal design;content
摘  要:
The preparation of lutein soft capsule was optimized by orthogonal design with evaluation indexes such as sedimentation ratio and redispersibility,by taking soybean oil as the disperse medium,beeswax as the suspending agent,and soybean phospholipid as the moistening agent.The results showed that the optimal proportion of soft capsule contents were made from lutein,zeaxanthin,soybean oil,beeswax and soybean phosphoilpid(14.4∶0.6∶80∶1∶4)and the contents of soft capsule were well-distributed with good stabilization and fluidity.

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