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魔芋粉片剂的制备研究

作  者:
王雪莹;蒋丽;钟耕;罗金华
单  位:
西南大学食品科学学院;重庆市生物技术研究所
关键词:
魔芋粉;片剂;制备
摘  要:
目的:研制魔芋粉片剂。方法:在用单因素实验选择崩解剂和填充剂的基础上,采用以硬度和崩解时限为指标的正交实验设计确立最佳配方。结果:选用8%羧甲基淀粉钠(CMS-Na)、0.3%硬脂酸镁、3%聚维酮K30、30%可压性淀粉(PCS),所得片剂崩解性能优良,各项指标均符合《中国药典》2005版相关规定。
译  名:
Preparation of konjac flour tablets
作  者:
WANG Xue-ying1,JIANG Li1,ZHONG Geng1,,LUO Jin-hua2(1.College of Food Science,Southwest University,Chongqing 400715,China;2.Biotechnological Institute of Chongqing,Chongqing 400222,China)
关键词:
konjac flour;tablets;preparation
摘  要:
Objective:To prepare konjac flour tablets.Method:Design single factor tests to compare different disintegrants and filler.Then,disintegration time and hardness as index,the formulation of konjac flour tablets was optimized by orthogonal design test.Results:The optimized konjac flour tablets,which were prepared by selecting 8% CMS-Na,0.3% magnesium stearate,3% K30,30% PCS.The disintegration of above formulation was excellent,and all its indexes were conformed to the requirement of China Pharmacopoeia.

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