当前位置: 首页 > 文章 > CRP与急性脑梗死神经功能的关系 石河子大学学报(自然科学版) 2008,38 (3) 325-327
Position: Home > Articles > Relation Between C-reactive Protein and Neuro-function Deficite of Acute Cerebral Infarction Journal of Shihezi University(Natural Science) 2008,38 (3) 325-327

CRP与急性脑梗死神经功能的关系

作  者:
朱凌云;孙侃;李晓军
单  位:
石河子大学医学院第一附属医院
关键词:
C反应蛋白;脑梗死;神经功能缺损评分
摘  要:
探讨C反应蛋白(CRP)与急性脑梗死神经功能的关系。对192例资料完整的急性初发脑梗死患者进行临床调查,包括既往史、一般特征(年龄、性别、腰臀比、体重指数)、血压、脑CT或MRI(梗死的部位及分型)、实验室检查(血糖、糖化血红蛋白、血脂、纤维蛋白原、CRP、尿酸),入院时采用欧洲卒中量表(ESS)来评价神经功能。对危险因素与脑梗死神经功能评分进行单因素、多因素分析。CRP与急性脑梗死神经功能损伤评分呈负相关关系;对脑梗死神经功能评分进行多因素分析显示:大面积脑梗、腔隙性脑梗死、CRP是脑梗死神经功能评分有意义的影响因素。CRP在这些因素中其重要性排第三。由此可知,ESS受其他因素影响,CRP不是全面评价急性脑梗死神经功能严重程度的一个指标。
译  名:
Relation Between C-reactive Protein and Neuro-function Deficite of Acute Cerebral Infarction
作  者:
ZHU Ling-Yun,SUN Kan,LI Xiao-jun(First Affiliated Hospital,College of Medicine,Shihezi University,Shihezi,Xinjiang 832008,China)
关键词:
C-reactive protein;cerebral infarction;European Stroke Scale
摘  要:
To investigate if the C-reactive protein(CRP)can be taken as a great marker that can reflect the severity of neuro-function deficite of acute cerebral infarction patients.192 patients clinic files including history,age,sex,systolic blood pressure(SBP),diastolic blood perssure(DBP),waist to hip ratio(WHR),body mass index(BMI),brain CT and MRI,the level of fasting plasma glucose(FPG),HbA1c,dyslipidemia and fibrinogen were investigated.we used European Stroke Scale(ESS)to evaluate neuro-function deficite.Simple regression analysis was used between ESS and CRP,multiple regression analysis was used between ESS and risk factors.simple regression analysis between ESS and CRP indicate that ESS has a negative correlation with CRP,multiple regression analysis indicate that size of infarction,lacunar infarct,CRP all contribute to neuro-function deficite and the CRP rank the third.ESS is influenced by many factors,CRP is not a great maker to assess the severity of neuro function deficite.

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