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Position: Home > Articles > Research Development in Production of Recombinant Vaccine Based on Fowlpox Virus Vector Progress in Veterinary Medicine 2002,23 (1) 34-37

应用禽痘病毒表达载体研制重组疫苗的研究进展

作  者:
乔传玲;袁远;于康震
单  位:
中国农业部畜牧兽医局;中国农业科学院哈尔滨兽医研究所兽医生物技术国家重点实验室;河南农业大学牧医工程学院
关键词:
禽痘病毒;重组;载体
摘  要:
禽痘病毒是继痘苗病毒之后又一种重要的动物病毒表达载体,它具有严格的宿主特异 性和生物安全性,从而使它成为禽类病原基因工程活载体疫苗研制过程中的一种应用极为广 泛的工具;同它在其它哺乳动物乃至人类病原基因的表达方面也显示了其独特的优越性及广 阔的开发和应用前景。本文对禽痘病毒作为表达载体的研究进展、应用前景及目前所存 在的问题作了综述。
译  名:
Research Development in Production of Recombinant Vaccine Based on Fowlpox Virus Vector
作  者:
QIAN Chuan-ling1, YUAN Yuan2, YU Kang-zhen3 (1.National Key Laboratory of Veterinary Biotechnology, Harbin Veterina ry Research Institute of Chinese Academy ; of Agricultural Sciences, Harbin, 150001,China; 2 . Henan Agricultural University, Zhengzhou, 4
关键词:
fowlpox virus; recombinant; vector
摘  要:
Fowlpox virus was an expressing vector based on live -virus, followed b y vaccinia virus. It was host-specific to avian species, which made it more sui t able than other vector for use as poultry vaccine vectors because of no risk of FPV outside the extend target species. Meanwhile, fowlpox virus has also become an important vector to successfully express the protective immunogen genes from several mammals- as well as human-origin viruses. So the research development s, application prospects and problems remained in this field were reviewed in the p resent paper.

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