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当前位置: 首页 > 文章 > 猪等孢球虫感染仔猪血液生理生化指标动态变化 河南农业大学学报 2008,42 (3) 306-312
Position: Home > Articles > Dynamic Observation on the Blood Physiological Index and Serum Biochemical Values of Piglets Infected with Isospora suis Journal of Henan Agricultural University 2008,42 (3) 306-312

猪等孢球虫感染仔猪血液生理生化指标动态变化

作  者：
宁长申;WANG Fang;王芳;张龙现;崔会玲;朱静静;姚雷;菅复春;李祥瑞
单  位：
南京农业大学动物医学院;河南农业大学牧医工程学院;郑州大学第二附属医院检验科
关键词：
猪等孢球虫;生理生化指标;仔猪
摘  要：
应用纯种猪等孢球虫(Isospora suis)孢子化卵囊人工感染9头6日龄仔猪,检测了感染前1 d和感染后1,3,6,9,11 d时血液生理生化指标.结果表明,仔猪感染I.suis后,白细胞数在感染后1 d开始增多,11 d达最高;红细胞在感染后3 d开始减少,9 d最低,11 d时恢复到感染前水平.血清丙氨酸氨基转移酶活性逐渐升高,感染后11 d时达最高值;天冬氨酸转氨酶感染后6 d升高并达到最高;感染后1 d碱性磷酸酶活性下降,11 d最低;血清乳酸脱氢酶、γ-谷氨酰转肽酶、α-羟丁酸脱氢酶活性均呈下降趋势,但无显著差异.感染后1 d时白蛋白含量下降,至11 d恢复到正常水平;球蛋白含量持续下降,但差异不显著.血清葡萄糖含量升高但无显著变化.感染后1~3 d时血清尿素氮含量降低,之后逐渐升高,至11 d时达最高;尿酸在感染后1~3 d升高,之后持续下降,至11d时最低.血清总胆固醇持续降低;甘油三酯在感染后1~9 d升高,11d时恢复到感染前水平.血清K+含量在感染后持续降低,但差异不显著.嗜中性白细胞,单核细胞,血红蛋白含量,红细胞压积,总蛋白含量,Na+,C l-,Ga2+,Mg2+含量均无明显变化.
译  名：
Dynamic Observation on the Blood Physiological Index and Serum Biochemical Values of Piglets Infected with Isospora suis
作  者：
NING Chang-shen1,2,WANG Fang2,ZHANG Long-xian2,CUI Hui-ling3,ZHU Jing-jing2,YAO Lei2,JIAN Fu-chun2,LI Xiang-rui1(1.College of Veterinary Science,Nnanjing Agricultural University,Nnanjing 210095,China;2.College of Animal Husbandry and Veterinary Science,Henan Agricultural University,Zhengzhou 450002,China;3.Test Department of Second Affiliated Hospital,Zhengzhou University,Zhengzhou 450014,China)
关键词：
Isospora suis;physiological index and serum biochemical values;piglet
摘  要：
In order to reveal the dynamic changes of the blood physiological index and serum biochemical values of piglets infected with Isospora suis,nine sixday-old piglets were inoculated with I.suis sporulated occysts.The blood physiological index and serum biochemical values were checked.The checked-time are 1 day before and 1,3,6,9,11 days post-infection(DPI),respectively.The results show that white blood cell rose on 1 DPI and reached peak value on 11 DPI.Red blood cell reduced on 3 DPI and came to the lowest point on 9 DPI,which was refection on 11 DPI.Alanine aminotransferase activity rose gradually and reached peak value on 11 DPI.Aspartate aminotransferase became the peak value on 6 DPI.Alkaline phosphatase descented on 1 DPI,and came to the lowest point on 11 DPI.Lactate dehydrogenase,γ-glutamyltransferase and α-hydroxybutyrate dehydrogenase were reduced but had no significant change.Albumin reduced on 1 DPI,which was refection on 11 DPI.Globulin decreased,but has no significant change.Glucose rose but has no significant change.Blood urea nitrogen decreased on 1～3 DPI,then rose gradually up to 11 DPI.Uric acid rose on 1～3 DPI,then deduced until 11 DPI.Total cholesterol decreased.Triglyeride rose on 1～9 DPI and returned to pre-infection level on 11 DPI.K+ content reduced on post infection but the difference was not obvious.However,leucocyte neutrophil,lymphomonocyte,hemoglobin,haematocrit,total protein,Na+,Cl-,Ga2+ and Mg2+ didn′t have significant change.

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