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当前位置: 首页 > 文章 > 猪等孢球虫研究进展 动物医学进展 2019 (6)
Position: Home > Articles > 猪等孢球虫研究进展 Progress in Veterinary Medicine 2019 (6)

猪等孢球虫研究进展

作  者：
戚南山;康桦华;林栩慧;吴彩艳;吕敏娜;李娟;胡俊菁;肖文婉;廖申权;孙铭飞
关键词：
猪等孢球虫;生活史;免疫学;基因组学;相互作用
摘  要：
猪等孢球虫是一种能引起仔猪球虫病的专性寄生性原虫,可引起仔猪严重腹泻甚至死亡,其发病率可高达50%~75%,病死率高达75%,呈世界性流行,严重危害养猪业发展.目前对仔猪球虫病的防控主要以药物预防为主,随着耐药虫株的不断产生及公众对药物残留的高度关注,使得这一防控手段面临巨大挑战,新型抗猪球虫药物、疫苗及其他防控手段亟待研究开发.论文对猪等孢球虫的生活史、基因组学、免疫学及其与其他微生物的互作关系等方面进行综述,以期为仔猪球虫病的综合防控提供参考.
作  者：
QI Nan-shan;KANG Hua-hua;Lin Xu-hui;WU Cai-yan;LV Min-na;LI Juan;HU Jun-jing;XIAO Wen-wan;LIAO Shen-quan;SUN Ming-fei;Institute of Animal Health,Guangdong Academy of Agricultural Sciences,Scientific Observation and Experiment Station of Veterinary Drugs and Diagnostic Techniques of Guangdong Province,Ministry of Agriculture,Key Laboratory of Livestock Disease Prevention of Guangdong Province;
单  位：
QI Nan-shan%KANG Hua-hua%Lin Xu-hui%WU Cai-yan%LV Min-na%LI Juan%HU Jun-jing%XIAO Wen-wan%LIAO Shen-quan%SUN Ming-fei%Institute of Animal Health,Guangdong Academy of Agricultural Sciences,Scientific Observation and Experiment Station of Veterinary Drugs and Diagnostic Techniques of Guangdong Province,Ministry of Agriculture,Key Laboratory of Livestock Disease Prevention of Guangdong Province
关键词：
Isospora suis;;life cycle;;immunology;;genomics;;interactions
摘  要：
Piglet coccidiosis is a parasitic protozoan disease caused by Isospora(Cystoisospora) suis,which can cause severe diarrhea and even death in piglets,the morbidity can be as high as 50%-75%,and the mortality is as high as 75%,it leads to considerable economic losses to the swine industry worldwide.In the present,the control of piglet coccidiosis is accomplished by synthetic chemical drug with toltrazuril which is highly effective.However,the emerging problems of anticoccidial resistance and drug residue are of concern regarding piglet coccidiosis,and it is an urgent need to develop new and effective drugs,vaccines or other alternative intervention strategies.This article reviewed the life cycle,genomics,immunity and interactions with other microorganisms in I.suis,in order to provide guidance for the prevention and control of coccidiosis in piglets.

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