译 名：
A Joint Susceptibility Test for Imipenem and Ceftriaxone
作 者：
Fu Honglei 1 ,Li Yan 1 ,Wang Tao 2 ,Du Dongdong 2 ,Chang Weishan 2 (1.Qingdao Feed and Veterinary Drug Testing Station,Qingdao,266071,China; 2.Animal scientific department of Shandong Agricultural University,Tai’an,271018)
关键词：
Imipenem;Ceftriaxone sodium;Antimicrobial susceptibility test;Resistance
摘 要：
to survey the antimicrobial effect jointed in vitro of the imipenem and ceftriaxone sodium ,escherichia coli of the gramnegative bacteria and tetrads of the gram-positive bacteria.combine different concentrations of the imipenem and ceftriaxone sodium to test antibacterial effect on e. coli and tetrads by the method of 8×8 chessboard,and calculated FIC values.Through this experiment, studies have shown that combination therapy significantly reduced the doage of imipenem and ceftriaxone. Efficiency of imipenem for E. coli can be 8 times and the efficiency for the tetrads can be 4 times. Ceftriaxone can be synergistic against E. coli and tetrads 16 times. Imipenem and ceftriaxone for the two bacteria drug FIC values were less than 0.5,was synergy.
