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Position: Home > Articles > The Latest Research Progress on CRISPR/Cas System Biotechnology Bulletin 2017,33 (2) 53-58

CRISPR/Cas系统最新研究进展

作  者:
刘妮;陆沁;刘娟;陈航
单  位:
中国林业科学研究院资源昆虫研究所;国家林业局资源昆虫培育与利用重点实验室
关键词:
基因组编辑技术;CRISPR/Cas系统;Cas9;scRNA
摘  要:
CRISPR/Cas系统为细菌与古细菌中抵御外源病毒和质粒DNA入侵的获得性免疫机制系统。作为一种新型的基因组编辑技术,具有设计简单、特异性强、效率高等优点,为基因组定向改造调控和应用带来了突破性的革命。就CRISPR/Cas系统的研究背景、存在类型以及TypeⅡ和TypeⅢCRISPR系统的基本作用原理和新的研究突破做了较为详尽的介绍,以便为读者和相关领域的研究者提供参考。
译  名:
The Latest Research Progress on CRISPR/Cas System
作  者:
LIU Ni;LU Qin;LIU Juan;CHEN Hang;The Research Institute of Resources Insects,the Chinese Academy of Forestry;Key Laboratory of Cultivation and Utilization of Resource Insects,State Forestry Administration;
关键词:
genome editing technology;;CRISPR/Cas system;;Cas9;;scRNA
摘  要:
The CRISPR/Cas is a system of immune mechanism for bacteria and archaea against exogenous virus and plasmid DNAinvasion. As a novel genome editing technology,it possesses the advantages of a simple design,strong specificity,and high efficiency,bringing revolutionary breakthrough for genome directional modification,regulation and application. We introduce the research background,the existence type of the CRISPR/Cas system,and basic action mechanism of Type II and Type III CRISPR system and new researchbreakthrough in detailed,for providing the reference for readers and researchers in related fields.

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