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Position: Home > Articles > Effect of Fangfushengji ointment on expression levels of VEGF and bFGF mRNA in wound tissues Journal of Traditional Chinese Veterinary Medicine 2011,13 (5) 5-7

防腐生肌膏对创伤组织中VEGF及bFGF mRNA表达水平的影响

作  者:
王卓然;戈胜;于文会
单  位:
东北农业大学动物医学学院
关键词:
大鼠;防腐生肌膏;VEGF;bFGF;创伤愈合
摘  要:
试验以Wistar大鼠为研究对象,通过对皮肤缺损模型大鼠创面组织中VEGF及bFGF mRNA表达水平等指标的检测,初步揭示防腐生肌膏促进创伤愈合的作用机制。试验结果表明,防腐生肌膏能提高创面组织VEGF和bFGF mRNA表达水平,从而可以促进血管内皮细胞和成纤维细胞的增殖和分化,促进创伤愈合。
译  名:
Effect of Fangfushengji ointment on expression levels of VEGF and bFGF mRNA in wound tissues
作  者:
WANG Zhuo-ran,GE Sheng,YU Wen-hui(College of Veterinary Medicine,Northeast Agricultural University,Harbin Heilongjiang 150030,China)
关键词:
rats;Fangfushengji ointment;VEGF;bFGF;wound healing
摘  要:
Wistar rat models with skin wound were established.Then the expression level of VEGF and bFGF mRNA were detected to reveal the mechanism of Fangfushengji ointment to promote wound healing.The results showed that Fangfushengji ointment could improve VEGF and bFGF mRNA levels in wound tissues,by which to promote the proliferation and differentiation of vascular endothelial cell and fibroblast,and thus promote wound healing.

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