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啶磺草胺的合成概述

作  者:
钱日彬;张大永
单  位:
中国药科大学药物科学研究院
关键词:
啶磺草胺;除草剂;三唑并嘧啶磺酰胺;合成方法
摘  要:
啶磺草胺是三唑并嘧啶磺酰胺类除草剂,总结了啶磺草胺及其中间体的合成路线和具体合成方法。啶磺草胺主要有2条合成路线,其中之一是由关键中间体2-氨基-5,7-二甲氧基[1,2,4]三唑并[1,5-a]嘧啶与2-甲氧基-4-三氟甲基-3-吡啶磺酰氯进行反应得到。
译  名:
A Review of Synthetic Methods of Pyroxsulam
作  者:
QIAN Ri-bin;ZHANG Da-yong;Drug Research Institute, China Pharmaceutical University;
关键词:
pyroxsulam;;herbicide;;triazolopyrimidine sulfonamide;;synthetic method
摘  要:
Pyroxsulam is a herbicide with chemistry of triazolopyrimidine sulfonamides. The synthetic methods and detailed processes of pyroxsulam and its intermediates were summarized in this paper. There were mainly two different synthetic routes for the preparation of pyroxsulam. Preferably, it was prepared by the reaction of 2-amino-5,7-dimethoxy[1,2,4]triazolo[1,5-a]pyrimidine with 2-methoxy-4-trifluoromethyl-3-pyridinesulfonyl chloride.

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