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Position: Home > Articles > Research Progress on LYZ and its Gene in the Animal Kingdom China Cattle Science 2012,38 (3) 55-58+63

动物溶菌酶基因的研究进展

作  者:
孙国庆;哈福;苗永旺;李大林
单  位:
云南农业大学动物科学与技术学院;云南省家畜改良工作站
关键词:
溶菌酶;基因;多态性;牛科物种;乳房炎
摘  要:
溶菌酶[Lysozyme(EC3.2.1.17),LYZ]是机体先天免疫系统中一个重要的效应分子,参与机体多种免疫反应,在溶菌过程中形成一个水解体系,破坏和消除侵入动物体内的病原,从而实现机体的免疫防御。它可以有效抑制葡萄球菌、大肠杆菌等一系列病原菌,是重要的奶牛乳房炎抗性因子之一。本文综述了溶菌酶基因的研究进展,包括其结构与进化、变异及应用前景等。
译  名:
Research Progress on LYZ and its Gene in the Animal Kingdom
作  者:
SUN Guo-qing1,HA Fu1,MIAO Yong-wang1,LI Da-lin2(1.College of Animal Science and Technology,Yunnan Agricultural University,Kunming 650201;2.Domestic Animal Breeding and Crossbreed Improvement Station,Kunming,Yunnan 650225)
关键词:
lysozyme;gene;polymorphism;bovine species;mastitis
摘  要:
Lysozyme(LYZ,EC3.2.1.17) is a key effective factor in body innate immune system,which participates in many kinds of body innate immune response.Lysozyme forms a hydrolyzed system when it plays a role in bacteriolysis.It damages and eliminates bacterial pathogens to realize body immune defense.Lysozyme is an important resistant factor of cow mastitis because of its effective inhibitory effect for many pathogenic bacteria such as Staphylococcus and Escherichia coli.This article reviews the advance of lysozyme gene features and its evolution,gene polymorphism and application prospect in animals.

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