当前位置: 首页 > 文章 > 猪肉中13种磺胺类药物多残留检测超高效液相-串联质谱法 中国农业科技导报(中英文) 2009,11 (1) 35-38
Position: Home > Articles > Simultaneous Determination of 13 Sulfonamides in Porcine Meat by Ultra Performance Liquid Chromatography-Tandem Mass Spectrometry Journal of Agricultural Science and Technology 2009,11 (1) 35-38

猪肉中13种磺胺类药物多残留检测超高效液相-串联质谱法

作  者:
严凤;曹莹;李丹妮;张文刚;蒋音;张鑫;顾欣
单  位:
上海兽药饲料检测所
关键词:
磺胺;残留分析;超高效液相-串联质谱
摘  要:
建立了用超高效液相-串联质谱仪检测猪肉中种磺胺多残留的方法。采用乙腈提取,正己烷去脂,碱性氧化铝柱净化后,用超高效液相-串联质谱仪进行定性及定量分析。方法最低检出限为0.25μg/kg。方法灵敏、准确,可实现多种磺胺激素同时进行定性及定量分析。
译  名:
Simultaneous Determination of 13 Sulfonamides in Porcine Meat by Ultra Performance Liquid Chromatography-Tandem Mass Spectrometry
作  者:
YAN Feng,CAO Ying,LI Dan-ni,ZHANG Wen-gang,JIANG Yin,ZHANG Xin,GU Xin(Shanghai Supervisory Institute of Veterinary Drugs and Feedstaff,Shanghai 201103,China)
关键词:
sulfonamide;residues analysis;ultra performance liquid chromatography-tandem mass spectrometry
摘  要:
A ultra performance liquid chromatography-tandem mass spectrometric(UPLC/MS/MS) method was developed for simultaneous determination of 13 sulfonamides in the porcine meat.Components were extracted from homogenized sample with acetonitrile,defatted by n-hexane and further extracted by Alumia B.The limit of determination(LOD) was 0.25 μg/kg.The method was proved to be satisfactory in precision,securacy and sensitivity for multi-residues determination.

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