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高效液相色谱法测定婴幼儿乳粉中烟酰胺的不确定度评定

作  者:
霍艳敏;王艳丽;王骏;周莉莉;祝建华;张卉;薛霞
单  位:
山东省产品质量监督检验研究院国家加工食品质量监督检验中心(山东)
关键词:
不确定度;烟酰胺;婴幼儿乳粉;高效液相色谱法
摘  要:
建立高效液相色谱法测定婴幼儿乳粉中烟酰胺不确定度的数学模型,并根据JJF 1135—2005《化学分析测量不确定度评定》和JJF 1059—1999《测量不确定度评定与表示》中的有关规定,逐层对乳粉中烟酰胺测量不确定度来源进行评估,最后给出合成标准不确定度和扩展不确定度;婴幼儿乳粉中烟酰胺测定结果为(63.01±3.50)mg/kg,k=2,p=95%。通过评定,提出影响检测结果的主要因素为样品前处理过程、标准溶液、标准曲线拟合等。
译  名:
Uncertainty Evaluation for Nicotinamide Determination in Infant Formula Milk Powder by High Performance Liquid Chromatography
作  者:
HUO Yan-min,WANG Yan-li,WANG Jun,ZHOU Li-li,ZHU Jian-hua,ZHANG Hui,XUE Xia(National Center for Quality Supervision and Inspection of Processed Food(Shandong),Shandong Supervision and Inspection Institute for Product Quality,Jinan 250103,China)
关键词:
uncertainty;nicotinamide;infant formula milk powder;high performance liquid chromatography(HPLC)
摘  要:
A mathematical model was established to evaluate the uncertainty of determining nicotinamide in infant formula milk powder by high performance liquid chromatography with diode-array detection.According to the relevant regulations given in JJF 1135-2005 Evaluation of Uncertainty in Chemical Analysis Measurement and JJF 1059-1999 Evaluation and Expression of Uncertainty in Measurement,the sources of uncertainty for determining nicotinamide in infant formula milk powder were explored.Finally,the standard uncertainty and the expanded uncertainty were achieved.The content of nicotinamide in infant formula milk powder determined by HPLC was(63.01 ± 3.50) mg/kg.The major sources of uncertainty affecting determination results were pre-treatment,standard solution and standard curve fitting.

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