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Position: Home > Articles > The New Improvement of Imidacloprid Synthesize in Recent Years Agrochemicals 2009,48 (7) 469-470+486

近年来吡虫啉合成新进展

作  者:
程志明
单  位:
上海生农生化制品有限公司
关键词:
吡虫啉;2-氯-5-氯甲基吡啶;合成
摘  要:
叙述了2000年以来2-氯-5-氯甲基吡啶和吡虫啉的多种合成方法。2-氯-5-氯甲基吡啶的合成采用环戊二烯环合法,需研发有利于环境的绿色生产工艺,减少三废,治理三废。以3-甲基吡啶为原料一步氯化成2-氯-5-氯甲基吡啶的工艺应进一步改进。吡虫啉合成中用五氧化二磷脱水法和过量2-硝基亚氨基咪唑烷法收率接近90%,纯度达95%以上,是较佳的合成方法。
译  名:
The New Improvement of Imidacloprid Synthesize in Recent Years
作  者:
CHENG Zhi-ming(shanghai shengnong Pesticide co.,ltd.,shanghai 201100,china)
关键词:
imidacloprid;2-chloro-5-chlormethylpyridine;preparation
摘  要:
The synthesis methods of 2-chloro-5-chlormethylpyridine and imidacloprid from 2 000 were reviewed.The process of preparation for 2-chloro-5-chlormethylpyridine by cyclopentadiene cyclization needs to do more research by using green process and decreasing the wastes.The process of 2-chloro-5-chlormethylpyridine from 3-methylpyridine in one-step chlorination should be further improved.During the process of imidacloprid preparation,using phosphorus pentachloride dehydration and greatly excess 2-nitroiminoimidazolidine,the yield may reach 90%,and the purity is over 95%,so this a fairly good synthesis method.

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