关键词：
慢性应激;地塞米松;维生素;微量元素;山羊
摘 要：
为了研究慢性应激对体内维生素和微量元素的影响,试验选用10只装有永久性瘤胃瘘管的波杂公山羊,随机均分为对照组和处理组,对照组肌注生理盐水,处理组肌注地塞米松0.2 mg/kg,每天注射1次,连续21 d。分别在第1、7、14和21天采集瘤胃液和血液样品,屠宰后采集相关组织样品。结果显示:处理组肝脏指数有上升趋势(P=0.07),脾脏指数极显著下降(P<0.01)。对于维生素,处理组肝脏VE(P=0.077)和VC(P=0.066)含量有升高的趋势,处理组血浆中VA(P<0.05)和视黄醇结合蛋白(P<0.01)含量显著升高。对于微量元素,处理组肝脏Mn含量有升高趋势(P=0.075),处理组十二指肠中Fe含量有下降的趋势(P=0.09),处理组结肠和盲肠组织Cu含量显著升高(P<0.05);结肠内容物中Cu含量极显著下降(P<0.01);瘤胃液中Fe含量在第1天显著低于对照组(P<0.05),但在第21天极显著高于对照组(P<0.01),瘤胃液中锰含量仅在第14天显著低于对照组(P<0.05)。研究结果表明,慢性应激能够引起山羊体内维生素和微量元素发生变化,为接下来更进一步的研究提供了参考。
译 名：
Effects of dexamethasone on the contents of several vitamins and trace elements in goats
作 者：
CHEN Qu;HUA Canfeng;NIU Liqiong;GENG Yali;NI Yingdong;Key Laboratory of Animal Physiology and Biochemistry,Ministry of Agriculture,Nanjing Agricultural University;
关键词：
chronic stress;;dexamethasone;;vitamins;;trace elements;;goats
摘 要：
The aim of this experiment was to assess the effects of dexamethasone on the content of vitamins and trace elements in goats. Ten rumen-cannulated boer goats were randomly and equally assigned to the control and treatment groups. The control group was injected with0. 2 mg/kg of saline,and the treatment group with 0. 2 mg/kg of dexamethasone,once a day for 21 days. Then,blood and rumen fluid samples were collected on the 1 st,7 th,14 thand 21 stdays respectively,and tissue samples were collected after slaughter. The results showed that,compared with the control group,the treatment group had an increasing trend in the liver index( P = 0. 07) but a significant decrease in the spleen index( P<0. 01). For vitamins,compared with the control group,the contents of vitamins C( P = 0. 077) and E( P = 0. 066) in the liver of the treatment group had an increasing trend,and vitamin A( P< 0. 05) and the retinol binding protein( P< 0. 01) in their plasma were significantly increased. For trace elements,the content of Mn in the liver of the treatment group tended to increase( P = 0. 075),the content of Fe in their duodenum tended to decrease( P = 0. 09),the Cu contents in their colon and caecum significantly increased( P <0. 05),but The Cu in their colon significantly decreased( P<0. 01). On the 1 st day of the experiment,the iron content in the ruminant fluid in the treatment group was significantly lower than that in the control group( P<0. 05),but,on the 21 stday,it was very significantly higher( P<0. 01). The Mn content in the ruminant fluid of the treatment group significantly decreased only on the 14 thday,compared with the control group( P<0. 05). Our results suggest that chronic stress may alter the contents of vitamins and trace elements in goats,which provides a reference for further studies in future.
