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Position: Home > Articles > Process research on the reflux extraction of flavonoids from Rubus crataegifolius leaves. Medicinal Plant 2012,3 (6)

Process research on the reflux extraction of flavonoids from Rubus crataegifolius leaves.

作  者:
Tang Hong-mei;Chang LiXin;Ding Cun-bao;Shuhua Zhang;Jia Chang-hon
单  位:
College of Life Sciences,Hebei United University,Tangshan,Heibei 063000,Chin;College of Life Sciences,Hebei United University,Tangshan,Heibei 063000,China
关键词:
flavonoids;rate of;leaves;extraction time;solid-liquid ratio;extraction temperatur
摘  要:
[Objective] To study the optimum extraction condition of flavonoids from Rubus crataegifolius leaves by using reflux extraction method.[Method] Taking ethanol as the solvent,effects of ethanol concentration,solid-liquid ratio,extraction temperature,and extraction time on the extraction rate of flavonoids were studied.Based on the results of single factor test,orthogonal test was designed and the optimal technology condition was selected.[Result] Factors affecting the extraction rate of flavonoids were in the order of solid-liquid ratio ethanol concentration extraction temperature extraction time.The optimal extraction condition was as follows:70% ethanol,1:20(g/ml)solid-liquid ratio,85 ℃ extraction temperature and 1.5 h extraction time.Under this condition,the extraction rate of flavonoids was 9.51%.[Conclusion] Reflux extraction of flavonoids from R.crataegifolius leaves was simple and had relatively high extraction rate.

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