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Position: Home > Articles > 新鱼腥草素钠对脾细胞增殖及对其产生IL-2水平的影响 Chinese Journal of Veterinary Science 2013,33 (5) 727-729,737

新鱼腥草素钠对脾细胞增殖及对其产生IL-2水平的影响

作  者:
李乾学;夏志平;吴永魁;陈阳阳
单  位:
军事医学科学院军事兽医研究所
关键词:
新鱼腥草素钠;脾细胞;白细胞介素-2
摘  要:
MTT法检测新鱼腥草素钠对脾细胞的增殖反应,胸腺细胞增殖法检测新鱼腥草素钠对脾细胞分泌IL-2的影响.在脾细胞培养液含有2.5mg/L ConA的条件下,128及256mg/L新鱼腥草素钠能够促进脾细胞增殖,与2.5mg/L ConA组对照,经统计学检验,差异有显著性(P<0.01).64、128及256mg/L新鱼腥草素钠表现出提高脾细胞培养透析液中的IL-2水平的作用,与2.5mg/L ConA组比较,经统计学检验,差异有显著性(P<0.05或P<0.01).
单  位:
The Military Veterinary Institute,Military Academy of Medical Sciences,Changchun130122,China
关键词:
sodinm new houtluyfonate%splenocyte%IL-2
摘  要:
The action of sodium new houttuyfonate on the splenocyte proliferation was tested by MTT spectrophotometry,and the activity of sodium new houttuyfonate on the production of IL-2 from splenocytewas was investigated by measuring the proliferation of thymoeytes promoted by IL-2 from splenocyte.In condition that splenocyte culture solution contained 2.5 mg/L ConA,the proliferation and the level of IL-2 of splenocyte could be increased and promoted by 128 mg/L and 256 mg/L sodium new houttuyfonate.Compared with 2.5 mg/L ConA group,sodium new houttuyfonate groups have significant difference(P<0.05or P<0.01).

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