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Position: Home > Articles > The influence of Gynostemma Polysaccharide on the Spleen and Thymus of Mouse Hubei Agricultural Sciences 2013,49 (17) 4156-4160

绞股蓝多糖对小鼠胸腺和脾脏影响的研究

作  者:
周石琼;卢俊求;李桂芝;周悦;魏晓瑞;王晓丽
单  位:
广西大学动物科学技术学院;重庆市璧山县大路镇畜牧兽医站
关键词:
绞股蓝多糖;小鼠胸腺;脾脏;细胞凋亡;细胞增殖
摘  要:
采用原位末端标记(TUNEL)、过氧化物酶标记的链霉卵白素染色试剂盒(SP)技术,观察绞股蓝多糖对小鼠胸腺、脾脏淋巴细胞凋亡和增殖的影响。结果发现各组胸腺和脾脏中均可见凋亡的淋巴细胞,细胞胞核染色质固缩凝聚,有的形成凋亡小体。统计分析表明,50 mg/kg的绞股蓝多糖能促进胸腺和脾脏淋巴细胞的增殖和凋亡,推论可知其可以促进胸腺和脾脏淋巴细胞的更新。
译  名:
The influence of Gynostemma Polysaccharide on the Spleen and Thymus of Mouse
作  者:
ZHOU Shi-qiong;LU Jun-qiu;LI Gui-zhi;ZHOU Yue;WEI Xiao-rui;WANG Xiao-li;Dalu Veterinary Station of Bishan;College of Animal Science and Technology, Guangxi University;
关键词:
gynostemma polysaccharide;;thymus;;spleen;;cell apoptosis;;cell proliferation
摘  要:
The influence of gynostemma polysaccharide on lymphocyte apoptosis and proliferation of the spleen and thymus was detected by TUNEL and SP.The results showed the apoptosis cells were found in all groups of spleen and thymus,chromatin of the cell nucleus were pyknosis and cohesion,and some even formed the apoptotic body.The statistical analysis showed that 50 mg / kg gynostemma polysaccharide could promote the lymphocyte proliferation and apoptosis of the spleen and thymus.It indicated that the Gynostemma polysaccharide could provoke the renew of the spleen and the thymus lymph cell on physiological status.

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