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Position: Home > Articles > Introduction of Several Detection Methods for Creatine Kinase Animal Husbandry and Feed Science 2015,36 (8) 16-19

几种肌酸激酶的检测方法

作  者:
Yang Di
单  位:
Animal Husbandry Science
关键词:
ck;type;mi;isoenzyme;detection methods;muscula
摘  要:
肌酸激酶(creatine kinase,CK)是动物细胞代谢过程中非常重要的一种激酶,有4种同工酶。根据亚基和分布位置的不同,CK同工酶可分为:肌肉型(MM)、杂化型(MB)、脑型(BB)以及线粒体型(Mi Mi)。人和动物发生疾病时,机体内的CK通常会有显著提高并能被检测到,因此经常被应用于人和动物疾病的早期诊断。对几种常用的CK检测方法的原理进行了概述,并对不同检测方法进行了比较,以期为今后CK检测方法的改良和创新提供一定的理论基础。
译  名:
Introduction of Several Detection Methods for Creatine Kinase
作  者:
YANG Ding;ZHAO Shi-hua;WU Jiang-hong;WANG Xiao-juan;QI Yun-xia;SUN Hai-lian;Inner Mongolia Prataculture Research Center, Chinese Academy of Sciences;Institute of Veterinary Medicine, Inner Mongolia Academy of Agricultural & Animal Husbandry Sciences;
关键词:
creatine kinase;;mass method;;enzyme method;;electrophoresis method;;chromatography method;;comparison
摘  要:
Creatine kinase(CK) plays an important role in animal cell metabolism process and has 4 kinds of isoenzyme.According to the variation of subunits and distributive location, the isoenzyme of CK can be classified into four types: muscular type(MM), hybrid type(MB), brain type(BB) and mitochondrial type(Mi Mi). Since CK can reach a high level when human or animal get sick, so it is commonly used as a sign on early diagnosis of disease. The principle of several CK detection methods were introduced and compared, so as to lay a basis for improvement and innovation of CK detection method.

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