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Position: Home > Articles > A Study on Synthesis of 4-(Methylsulfonyl)-2-nitrobenzoic Acid Agrochemicals 2013 (3) 174-177

2-硝基-4-甲砜基苯甲酸的合成新工艺

作  者:
刘月中;王景国;邢颖;鄂彦鹏
单  位:
沈阳化工研究院有限公司
关键词:
甲基磺草酮;2-硝基-4-甲砜基苯甲酸;氧化
摘  要:
[目的]研究甲基磺草酮的重要中间体2-硝基-4-甲砜基苯甲酸的合成新方法。[方法]以邻硝基甲苯为起始原料,经过磺化、氧化,最后得到邻硝基对甲砜基苯甲酸的工艺路线。讨论合成工艺路线的优化及条件。[结果]制备成本降低至5万元/吨。[结论]该工艺简单经济,适合工业化生产。
译  名:
A Study on Synthesis of 4-(Methylsulfonyl)-2-nitrobenzoic Acid
作  者:
LIU Yue-zhong,WANG Jing-guo,XING Ying,E Yan-peng(Shenyang Research Institute of Chemical Industry Co.,Ltd.,Shenyang 110021,China)
关键词:
mesotrione;4-(methylsulfonyl)-2-nitrobenzoic acid;oxidation
摘  要:
A novel synthetic method of the important intermediate compound of mesotrione,4-(methylsulfonyl)-2-nitrobenzoic acid,was reported in detail.[Methods] The compound was synthesized from o-nitrobenzene by three steps including sulfonation,oxidation,and so on.The reaction condition was optimized.[Results] The cost of production was induced to $50?000 per ton.[Conclusions] Its preparing process is simple and low-cost,which is suitable for industrial scale manufacture.

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