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当前位置: 首页 > 文章 > 鲁中肉羊BMPR1B、BMP15和GDF9基因多态性与产羔数关联分析 中国草食动物科学 2019 (4) 1-5+10
Position: Home > Articles > Polymorphisms of BMPR1B,BMP15 and GDF9 Genes and Their Association with Litter Size in Luzhong Mutton Sheep China Herbivore Science 2019 (4) 1-5+10

鲁中肉羊BMPR1B、BMP15和GDF9基因多态性与产羔数关联分析

作  者：
孙庆;田志龙;刘秋月;潘林香;王金文;储明星
单  位：
中国农业科学院北京畜牧兽医研究所;济南市莱芜嬴泰农牧科技有限公司;中国农业科学院北京畜牧兽医研究所农业部动物遗传育种与繁殖重点实验室;山东省农业科学院畜牧兽医研究所
关键词：
鲁中肉羊;BMPR1B;BMP15;GDF9;分型;产羔数
摘  要：
为分析绵羊已知多羔主效基因BMPR1B、BMP15和GDF9的多态性与鲁中肉羊产羔数之间的关系,采用Sequenom MassARRAY誖SNP技术检测鲁中肉羊BMPR1B、BMP15和GDF9基因中已知主效位点多态性,并与产羔数进行关联分析。结果表明:BMPR1B基因在鲁中肉羊中存在FecB突变,GDF9基因6个分型位点仅4个位点(G1、G3、G4、G5)在鲁中肉羊中存在多态,BMP15基因中5个分型位点在鲁中肉羊中均不存在多态性。FecB基因3种基因型(CC、CT、TT)突变频率分别为0.16、0.58和0.26,此位点多态性较高(0.25
译  名：
Polymorphisms of BMPR1B,BMP15 and GDF9 Genes and Their Association with Litter Size in Luzhong Mutton Sheep
作  者：
Sun Qing;Tian Zhilong;Liu Qiuyue;Pan Linxiang;Wang Jinwen;Chu Mingxing;Key Laboratory of Animal Genetics,Breeding and Reproduction of Ministry of Agriculture,Institute of Animal Science,Chinese Academy of Agricultural Sciences;Jinan Laiwu Yingtai Agriculture and Animal Husbandry Technology Co.,Ltd.;Institute of Animal Science and Veterinary Medicine,Shandong Academy of Agricultural Sciences;
单  位：
Sun Qing%Tian Zhilong%Liu Qiuyue%Pan Linxiang%Wang Jinwen%Chu Mingxing%Key Laboratory of Animal Genetics,Breeding and Reproduction of Ministry of Agriculture,Institute of Animal Science,Chinese Academy of Agricultural Sciences%Jinan Laiwu Yingtai Agriculture and Animal Husbandry Technology Co.,Ltd.%Institute of Animal Science and Veterinary Medicine,Shandong Academy of Agricultural Sciences
关键词：
Luzhong mutton sheep;;BMPR1B gene;;BMP15 gene;;GDF9 gene;;genotyping;;litter size
摘  要：
To elucidate the association of polymorphisms of BMPR1 B,BMP15 and GDF9 genes and litter size in sheep. Luzhong mutton sheep were selected and Sequenom Mass ARRAY ?SNP assay was applied to genotype BMPR1 B,BMP15 and GDF9 genes.Then the association was analyzed between BMPR1 B,BMP15 and GDF9 genes and litter size in Luzhong mutton sheep. The typing results showed that there were FecB mutation in BMPR1 B gene and 4 mutations(G1,G3,G4,G5)in GDF9 gene. There were no polymorphisms of BMP15 in our population. FecB had CC,CT and TT genotypes,and the genotype frequencies were 0.16,0.58 and0.26,respectively. This locus showed medium polymorphism(0.25

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