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当前位置: 首页 > 文章 > 电针对正常犬血浆三种相关神经营养因子的影响 中国动物保健 2016,18 (3) 62-65
Position: Home > Articles > Effects of Electroacupuncture on Plasma Concentrations of Three Related Neurotrophic Factors in Normal Dogs China Animal Health 2016,18 (3) 62-65

电针对正常犬血浆三种相关神经营养因子的影响

作  者：
李伟;李拓;高蕊;程鹏;李佳;姜代勋;陈武
单  位：
兽医学(中医药)北京市重点实验室;北京农学院动物科学技术学院
关键词：
神经生长因子;脑源性神经营养因子;神经营养素3;电针
摘  要：
目的:初步观察电针对正常比格犬血浆中神经营养因子浓度的影响,为分析针灸对神经机能障碍性疾病的治疗、保健作用机制积累数据。方法:8只比格犬,选取足三里、趾间、百会和膀胱俞穴,于清醒状态下隔日电针刺激,并在电针前和首次电针后第1天、4天、7天和14天采血,分离血浆,Elisa试剂盒检测神经生长因子(nerve growth factor,NGF)、脑源性神经生长因子(brain-derived neurotrophic factor,BDNF)和神经营养素-3(neurotrophin-3,NT-3)的浓度。结果:电针后,血浆中三种神经营养因子的浓度呈升高变化。与针前比较,NGF的浓度在电针后第4天极显著升高(P﹤0.01)、第7天显著升高(P﹤0.05)和第14天极显著升高(P﹤0.01);BDNF的浓度在电针后第4天、第7天和第14天均极显著升高(P﹤0.01);NT-3的浓度在电针后第4天(P﹤0.01)和第14天(P﹤0.01)差异极显著,第1天和第7天差异不显著。结论:电针可提高犬血浆NGF、BDNF、NT-3的浓度,提示电针对神经系统的治疗与保健作用可能与此有关。
译  名：
Effects of Electroacupuncture on Plasma Concentrations of Three Related Neurotrophic Factors in Normal Dogs
作  者：
Li Wei;Li Tuo;Gao Rui;Cheng Peng;Li Jia;Jiang Daixun;Chen Wu;Department of Animal Science and Technology, Beijing University of Agriculture;Beijing Key Laboratory of Veterinary Medicine (Traditional Chinese Medicine and Pharmacology;
关键词：
NGFB;;DNF;;NT-3;;EA
摘  要：
Objective: To observe the preliminary effect of electroacupuncture(EA) on normal Beagle dogs' plasma concentrations of neurotrophic factors and accumulate data for analysing the mechanism of EA treatment and health effects on nerve dysfunction diseases. Methods: The acupoints of ST36(Zusanli) LR2(Zhijian) DU20(Baihui) BL28(Pangguangshu) of 8 normal beagles were stimulated at waking state, 25 minutes per time, every other day. Separated the plasma from blood before and at 1d, 4d, 7d, 14 d after EA. After that, measured the plasma concentrations of NGF, BDNF and NT-3 by using the Elisa kits. Results: The plasma concentrations of the three neurotrophic factors increased after EA. Compared with the blank group before EA, the concentration of NGF significantly increased at 4d and 14d(P﹤0.01), markedly increased at 7d(P﹤0.01); The concentration of BDNF significantly higher than blank group at 4d、7d and 14d(P ﹤0.01); The concentration of NT-3 has significant difference at 4d and 14d(P ﹤0.01) and with no difference at 1d and 7d.Conclusion: The plasma concentrations of NGF, BDNF and NT-3 can be increased by EA and this may related to the effect of EA on nerve system health and treatment.

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