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2-氯-5-氯甲基吡啶高效液相色谱分析

作  者:
董燕
关键词:
2-氯-5-氯甲基吡啶;高效液相色谱法;分析方法
摘  要:
建立2-氯-5-氯甲基吡啶高效液相色谱分析方法。采用Agilent SB-C_(18)色谱柱,流动相为乙腈-水(体积比50∶50),流速为1.0 mL/min,紫外检测波长270 nm条件下进行外标法定量。该方法在400~550 mg/L质量浓度范围呈良好线性,回收率为99.6%,相对标准偏差为0.418%,变异系数为0.42%。该方法操作简便,准确度和精密度高,线性相关性好。
译  名:
Analysis of 2-chloro-5-chloromethylpyridine by HPLC
作  者:
DONG Yan;State Key Laboratory of the Discovery and Development of Novel Pesticide,Shenyang Research Institute of Chemical Industry Co., Ltd.;
单  位:
DONG Yan%State Key Laboratory of the Discovery and Development of Novel Pesticide,Shenyang Research Institute of Chemical Industry Co., Ltd.
关键词:
2-chloro-5-chloromethylpyridine;;HPLC;;analysis method
摘  要:
A HPLC method for analysing 2-chloro-5-chloromethylpyridine was established. The sample was separated and analyzed quantitatively on Agilent SB-C_(18) 4.6 mm×150 mm×5 μm reversed-phase chromatography column and UV detector at 270 nm, using acetonitrile and water as the mobile phase. The rate of flow was 1.0 mL/min. Good linearity was obtained in range from 400-550 mg/L. The recovery rate was 99.6%. The results showed that the standard deviation of fenaminstrobin was 0.418. The variation coefficient was 0.42. The method was simple, rapid and accurate, and had good linear correlation.

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