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卵黄免疫球蛋白的应用进展

作  者:
史同瑞;李丹;姚瑞
单  位:
黑龙江省兽医科学研究所
关键词:
卵黄免疫球蛋白;作用机理;应用
摘  要:
卵黄免疫球蛋白是一种来源丰富的多克隆抗体。由于卵黄抗体不能激活哺乳动物的补体系统,不与哺乳动物的Fc受体、类风湿因子、葡萄球菌蛋白A和葡萄球菌蛋白G结合,因而作为诊断试剂具有较高的敏感性。卵黄抗体具有良好的免疫活性,作为防治药物具有见效快,疗效高,无毒副作用,无残留等优点,目前卵黄抗体已得到了广泛应用。本文综述了卵黄抗体在动物病毒性疾病、细菌性疾病和寄生虫病诊断、预防和治疗等方面的应用及前景。
译  名:
Application Progress on the Yolk Immunoglobulin
作  者:
SHI Tong-rui,Li Dan,Yao Rui (Heilongjiang Veterinary Science Research Institute,Qiqihaer 161006,China)
关键词:
yolk immunoglobulin;mechanism;application
摘  要:
The yolk immunoglobulin is a rich sources of polyclonal antibodies.The yolk immunoglobulin can not activate the complement system of mammalian,and it can not be combined with mammalian Fc receptors,rheumatoid factor,staphylococcal protein A and Staphylococcus protein G.Therefore it has a high sensitivity as a kind of diagnostic reagents.The yolk immunoglobulin has good immune activity.As a prevention drug,it has high efficacy,non-toxic side effect,non-residue.At present,The yolk immunoglobulin as a specific,efficient and inexpensive biological agent has been widely used in animal diseases.In this paper,the application and prospect were reviewed such as diagnosis,prevention and treatment in animal viral,bacterial and parasitic diseases.

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