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Position: Home > Articles > Nature and Characteristics of the Yolk Immunoglobulin Progress in Veterinary Medicine 2010,31 (2) 114-117

卵黄免疫球蛋白的性质与特点

作  者:
史同瑞;黄宇翔;苏永福
单  位:
黑龙江省兽医科学研究所
关键词:
卵黄免疫球蛋白;结构特点;理化性质;生物学特性
摘  要:
卵黄免疫球蛋白是一种产量高、成本低、易于生产、应用广泛的多克隆抗体,其稳定性良好,具有耐热、耐酸、耐碱和一定的抗酶解能力,因而利于临床保存和使用。卵黄抗体不能激活哺乳动物的补体系统,不与哺乳动物的Fc受体、类风湿因子(RF)、葡萄球菌蛋白A(SPA)、葡萄球菌蛋白G(SPG)结合,作为诊断试剂具有较高的敏感性。卵黄抗体具有良好的免疫活性,作为防治药物具有见效快,疗效高,无毒副作用,无残留等优点。目前,卵黄抗体作为特异、高效、价廉的生物制剂,已在动物疾病的免疫诊断、预防和治疗中得到了应用,随着有关研究的不断深入,其应用前景将会更为广阔。
译  名:
Nature and Characteristics of the Yolk Immunoglobulin
作  者:
SHI Tong-rui,HUANG Yu-xiang,SU Yong-fu(Heilongjiang Veterinary Science Research Institute,Qiqihaer,Heilongjiang,161006,China)
关键词:
yolk immunoglobulin;structure characteristic;physico-chemical nature;biology characteristic
摘  要:
The yolk immunoglobulin is a sort of polyclonal antibodies whose characteristics are high yield,low cost,easy production easily and wide use wide.With good stability in anti-heat,anti-acid,anti-alkali and anti-enzyme,it is good for storage and clinical usage. The yolk immunoglobulin can not activate the complement system of mammalian,and it can not be combined with mammalian Fc receptors,rheumatoid factor(RF),staphylococcal protein A(SPA)and staphylococcal protein G(SPG). As a kind of diagnostic reagents,it has a high sensitivity. The yolk immunoglobulin has good immune activity. As a prevention drug,it has high efficacy,non-toxic side effect,non-residue and so on. At present,the yolk immunoglobulin as a specific,efficient and inexpensive biological agent has been used in animal disease,diagnosis,prevention and treatment.

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