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Position: Home > Articles > The Effect of Different Surfactants on the SoLubiLity of SarafLoxacin HydrochLoride China Animal Health 2016 (12) 81-84

不同表面活性剂对盐酸沙拉沙星溶解度影响

作  者:
陈诚;童青平;唐达
单  位:
重庆市畜牧科学院
关键词:
表面活性剂;盐酸沙拉沙星;增溶
摘  要:
本文通过研究不同表面活性剂(OP-10、吐温-80、十二烷基吡咯烷酮)对盐酸沙拉沙星溶解度的影响,探讨不同表面活性剂分子结构对盐酸沙拉沙星增溶原理,并通过建立盐酸沙拉沙星含量测定标准曲线,量化增溶效果。实验结果表明,在OP-10用量为12%时,对盐酸沙拉沙星溶解度达到最大4.683ug/m L,具有较好效果。
译  名:
The Effect of Different Surfactants on the SoLubiLity of SarafLoxacin HydrochLoride
作  者:
Chen Cheng;Tong Qingping;Tang Da;ChongQing Academy of AnimaL Sciences;
关键词:
Surfactant;;SaLfLoxacin hydrochLoride;;SoLubiLization
摘  要:
The effects of different surfactants(OP-10, Tween-80 and dodecy L-pyrro Lidone) on the so Lubi Lity of sa Lf Loxacin hydroch Loride were studied in this paper. To exp Lore the so Lubi Lization mechanism of sa Laf Loxacin hydroch Loride by mo Lecu Lar structure of different surfactants, And the standard curves for the determination of sa Lf Loxacin hydroch Loride were estab Lished,quantitative so Lubi Lization effect. The resu Lts showed that the best so Lubi Lity of sa Lazacin hydroch Loride was 4.683 ug / m L when the dosage of OP-10 was 12%.

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