当前位置: 首页 > 文章 > 中药制剂对小鼠耐力及免疫器官指数影响 中兽医医药杂志 2010,29 (1) 14-17
Position: Home > Articles > Effects of traditional Chinese medicine preparation on the endurance and immune organ index in mice Journal of Traditional Chinese Veterinary Medicine 2010,29 (1) 14-17

中药制剂对小鼠耐力及免疫器官指数影响

作  者:
赵迎虎;张明军;刘进辉;孙志良;伍勇;彭涛
单  位:
湖南农业大学动物医学院
关键词:
免疫器官指数;耐力;单核巨噬细胞;CH50
摘  要:
为了探索中药制剂对动物免疫机能的影响,将6种中药提取物复方免疫增强剂A、B、C、D、E、F按高、中、低(1、2、3)3个浓度分别饲喂3-4周龄的昆明小鼠30d。每组随机挑选10只,分别进行小鼠耐力及免疫器官指数等指标的检测。结果表明,各组小鼠游泳时间均显著增加;F1实验小鼠的免疫器官指数显著增加;E3实验小鼠的碳粒廓清指数K显著增加;B3实验小鼠的补体总活性CH50显著增加;经统计学软件SPSS11.5单因素方差分析有显著性差异(P<0.05)。提示6种中药制剂均能增强小鼠的非特异性免疫力。
译  名:
Effects of traditional Chinese medicine preparation on the endurance and immune organ index in mice
作  者:
ZHAO Ying-hu,ZHANG Ming-jun,LIU Jin-hui,SUN Zhi-liang,WU Yong,PENG Tao(College of Veterinary Medicine,Hunan Agricultural University,Changsha Hunan 410128,China)
关键词:
Immune organ index;endurance;mononuclear macrophage;CH50
摘  要:
In order to study the effect of Chinese herb medicine preparations on the animals' immunodeficiency,six kinds of Chinese medicine preparations immunoenhancer marked A,B,C,D,E,and F were fed to 3-4 week-old Kunming mouse for 30 days with high,middle and low doses (1,2 and 3). 10 mice of each group were randomly selected to test on the ability of swimming and the immune organ index etc. The results showed that the immune organ index in group F1,clearance index K in group E3,CH50 in group B3,and the endurance of the trial groups fed with Chinese medicine preparation were improved,statistics software SPSS11.5 in one-way ANOVA analysis showed significant difference(P≤0.05) between the above-mentioned trial groups with control groups. The results suggested that traditional Chinese medicine preparation could improve the nonspecific immunity of mice.

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