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Position: Home > Articles > Studuies on the Physicochemical Identification and the Stability of Nicotinylsalicylic Acid Journal of Shihezi University(Natural Science) 2005,23 (1) 1-4

烟酰水杨酸的理化性质和稳定性研究

作  者:
张梅;刘洪海;吴越;杨光;丁一上;陈文
单  位:
石河子大学药物研究中心
关键词:
烟酰水杨酸;HPLC;稳定性
摘  要:
通过对烟酰水杨酸理化常数的测定 ,确定了该化合物的理化鉴别方法 ,同时建立HPLC法对烟酰水杨酸的稳定性进行了研究。该法操作简便、灵敏度高、准确性和重现性好。稳定性实验表明烟酰水杨酸对高热、高湿及光照稳定。
译  名:
Studuies on the Physicochemical Identification and the Stability of Nicotinylsalicylic Acid
作  者:
ZHANG Mei, LIU Hong-hai,WU Yue, DING Yi-shang, YANG Guang, CHEN Wen (Drug Research Center of Shihezi University,Shihezi,Xinjiang 832002,China)
关键词:
nicotinylsalicylic acid; HPLC; stability
摘  要:
This experiment studied the physicochemical identification by determinating physicochemical constants and the stability of notinylsalicylic acid by HPLC method.Nicotinylsalicylic acid,nicotinic acid and salicylic acid were determined by HPLC method.The method was easy,accurate and stable.Nicotinylsalicylic acid was stable under the conditions of higher temperature,higher humidity and stronger light.It was stable while stored at room temperature.

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