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Position: Home > Articles > Changes in Fatty Acids Among Colostrum,Transitional,and Mature Milk from Chinese Women Food and Nutrition in China 2017,23 (05) 54-58

不同时期母乳中脂肪酸水平的变化

作  者:
李慧;郭倩颖;柳鹏;张岩春;戴智勇;高莹;王军波
单  位:
北京大学人民医院;中国科学院上海生命科学研究院营养科学研究所;北京大学公共卫生学院营养与食品卫生学系;澳优乳业(中国)有限公司
关键词:
母乳;脂肪酸;饱和脂肪酸;单不饱和脂肪酸;多不饱和脂肪酸
摘  要:
目的:了解不同哺乳期母乳中各种脂肪酸水平的差异及其变化趋势,为母乳喂养及婴幼儿配方奶粉的配制提供科学依据。方法:收集2015年7月—2016年3月,在北京大学人民医院足月顺产的25~40岁产妇产后1~5d的初乳、6~10d的过渡乳和30d的成熟乳123份,采用气相色谱质谱联用法(GC-MS)检测母乳中的脂肪酸成分,分析母乳中各脂肪酸水平的差异及随时间的变化趋势。结果:随着泌乳时间的延长,C18∶0、C14∶1ω5、C18∶3ω6水平和ω-6/ω-3比例呈增高趋势;C24∶0、C16∶1ω9、C20∶1ω9、C20∶2ω6、C20∶3ω6、C20∶4ω6(AA)、C22∶2ω6、C22∶4ω6、C22∶5ω6、C22∶5ω3和C22∶6ω3(DHA)水平呈下降趋势,总体SFA含量逐渐增加,但无显著性意义;而PUFA尤其是ω-3 PUFA水平显著减少(P<0.05)。结论:母乳中的各种脂肪酸随着泌乳时间的延长而不断变化,新生儿喂养及配方奶粉的配制时应考虑母乳中各种脂肪酸含量的微观变化。
译  名:
Changes in Fatty Acids Among Colostrum,Transitional,and Mature Milk from Chinese Women
作  者:
LI Hui;GUO Qian-ying;LIU Peng;ZHANG Yan-chun;DAI Zhi-yong;GAO Ying;WANG Jun-bo;Department Of Nutrition and Food Hygiene,School of Public Health,Peking University;Beijing Key Laboratory of Toxicological Research and Risk Assessment for Food Safety,Peking University;Peking University People's Hospital;Ausnutria Dairy(China) Company Ltd;CAS Key Laboratory of Nutrition and Metabolism,Institute for Nutritional Sciences,Shanghai Institutes for Biological Sciences,Chinese Academy of Sciences;
关键词:
human milk;;fatty acids;;saturated fatty acids(SFA);;polyunsaturated fatty acids;;monounsaturated fatty acids
摘  要:
Objective To compare the levels of fatty acids among colostrum,transitional,and mature milk in Chinese women.Method We collected 72 human milk samples at postpartum 1~5d,6~10d,and 30d from 24 mothers delivering full-term infants in Beijing.Fatty acids were determined by gas chromatography-mass spectrometer(GC-MS).Result Over the three stages,levels of C18∶0,C14∶1ω5,C18∶3ω6 and the ratio ofω-6/ω-3 increased significantly,while levels of C24∶0,C16∶1ω9,C20:1ω9,C20∶2ω6,C20∶3ω6,C20∶4ω6(AA),C22∶2ω6,C22∶4ω6,C22∶5ω6,C22∶5ω3 and C22∶6ω3(DHA)decreased(P<0.05).On the whole,total saturated fatty acids(SFA)remained stable,and polyunsaturated fatty acids(PUFA)especiallyω-3 PUFA decreased significantly during the lactation(P<0.05).No significant changes were found in the level of totalω-6 PUFA.Conclusion Different fatty acids of human milk varied differently with lactating period.Therefore,the changes should be taken into account when feeding newborns banked human milk or human milk fortifiers and when designing infant formulas.

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