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当前位置: 首页 > 文章 > 预测酵母内含子中的转录调控元件(英文) 云南农业大学学报(自然科学) 2005,20 (1) 1-5+10
Position: Home > Articles > Predicting Potential Regulatory Elements of Transcription in Yeast Introns~ Journal of Yunnan Agricultural University(Natural Science) 2005,20 (1) 1-5+10

预测酵母内含子中的转录调控元件(英文)

作  者：
胡俊;韩莹;毛谨
单  位：
云南农业大学基础信息工程学院;云南农业大学外语学院;云南农业大学水利水电与建筑学院
关键词：
内含子;转录调控元件;酵母;期望频率
摘  要：
基于酵母基因非编码序列中寡核苷酸的出现频率 ,拟用期望频率法从转录效率较高的内含子序列中提取到一些过表达的寡核苷酸。将提取的寡核苷酸与其它方法获得的结果和试验证实的转录因子结合位点相比较 ,结果显示这些寡核苷酸可能是潜在的转录因子结合位点。这些推测有待试验的进一步证实
译  名：
Predicting Potential Regulatory Elements of Transcription in Yeast Introns~
作  者：
HU Ju~(1,2),HAN Ying~3,MAO Jin~4 ( 1. The Fundamental Information Engineering College, Yunnan Agricultural University, Kunming 650201,China; 2. The Center of Applied Statistics, Yunnan University, Kunming 650091,China; 3. College of Foreign Languages, Yunnan Agricultural University, Kunming 650201,China; 4. College of Water Resource Hydraulic Power and Architechture, Yunnan Agricultural University, Kunming 650201,China )
关键词：
introns; transcriptional regulatory element; yeast; expected frequency
摘  要：
Prediction of transcriptional regulatory elements in non-coding regions is an important and challenging problem. Based on the occurrence frequencies of oligonucleotides in the non-coding sequences of yeast genes, some over-represented oligonucleotides are extracted in the introns of high-transcribed yeast genes by expected frequency method. The extracted oligonucleotides are compared with the results obtained by other methods and transcription factor binding sites verified by experimental analyses.The results show that these over-represented oligonucleotides are likely to be potential binding sites for transcription factors. Further biological tests are needed to prove these assumptions.

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