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当前位置: 首页 > 文章 > 镧和精恶唑禾草灵对鲦红细胞微核及核异常的影响 水产科学 2007,26 (7) 408-410
Position: Home > Articles > The Effect of Lanthanum Chloride and Fenoxaprop-p-ethyl on Micronucleus and Nuclear Anomalies in Erythrocytes of Hemiculter leucisculus Fisheries Science 2007,26 (7) 408-410

镧和精恶唑禾草灵对鲦红细胞微核及核异常的影响

作  者：
张贵生
单  位：
菏泽学院生命科学系
关键词：
氯化镧;精恶唑禾草灵;鲦;红细胞;微核;核异常
摘  要：
鲦经过稀土元素镧和除草剂精恶唑禾草灵单独或联合作用24 h,结果表明:0.01~0.5 mg/L的La3+能显著抑制鲦红细胞微核及核异常的发生,不具遗传毒性;但当La3+质量浓度≥1 mg/L及精恶唑禾草灵均能明显诱导鲦红细胞微核及核异常的发生,与对照组相比,差异显著或极显著(P<0.05或P<0.01),具有遗传毒性。且精恶唑禾草灵质量浓度为0.01725~0.345 mg/L,微核率随浓度的增大而升高。0.01、0.1 mg/L的La3+与精恶唑禾草灵联合作用时的微核率明显低于精恶唑禾草灵而高于La3+单独作用时的微核率。而10 mg/L的La3+与精恶唑禾草灵联合作用时的微核率却明显低于二者单独作用时的微核率,二者呈拮抗作用;鲦是研究遗传毒理学的良好材料。
译  名：
The Effect of Lanthanum Chloride and Fenoxaprop-p-ethyl on Micronucleus and Nuclear Anomalies in Erythrocytes of Hemiculter leucisculus
作  者：
ZHANG Gui-sheng(Department of Life Sciences,Heze College,Heze 274015,China)
关键词：
lanthanum chloride;fenoxaprop-p-ethyl;Hemiculter leucisculus;erythrocytes;micronucleus nuclear anomalies
摘  要：
The author studied the effect of La3+and Fenoxaprop-p-ethyl on micronucleus and nuclear anomalies in erythrocytes of Hemiculter leucisculus.The results showed that La3+in low concentration(0.01～0.5 mg/L) significantly decreased the frequencies of micronuclei and nuclear anomalies.The frequency of micronuclei treated simultaneously by La3+and Fenoxaprop-p-ethyl were lower than that by Fenoxaprop-p-ethyl alone,and higher than that by La3+,alternatively.However,micronuclei and nuclear anomalies were induced by La3+in high concentration(≥1 mg/L).Treatment by the both reagents led to decrease the frequencies of the damaged items.Fenoxaprop-p-ethyl resulted in increase in the frequency of micronuclei in the H.leucisculus erythrocytes,and the frequency of micronucleated erythrocytes showed a dosage-dependent elevation in certain range of concentration(0.017 25～0.345 mg/L).The author found that H.leucisculus was sensitive to the mutants,and it can be used as a suitable material for study.

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