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Position: Home > Articles > Regulation Mechanism of Adiponectin Receptors Expression Chinese Journal of Animal Nutrition 2011,23 (10) 1651-1657

脂联素受体表达的调节机制

作  者:
罗佳捷;陈宇光;张彬;李丽立;杨永生
单  位:
中国科学院亚热带农业生态研究所动物生态营养与健康养殖联合实验室;湖南农业大学动物科学技术学院
关键词:
脂联素;脂联素受体;表达调节机制
摘  要:
脂联素是一种脂肪细胞分泌的蛋白因子,在人和动物体内通过其受体的介导来发挥多种生理功能,尤以增敏胰岛素、调节糖代谢和脂代谢、保护内皮细胞和对抗炎症等作用重大。本文就脂联素受体1和2的结构和分布、影响它们表达的因素及其机制的进行了综述。
译  名:
Regulation Mechanism of Adiponectin Receptors Expression
作  者:
LUO Jiajie1 CHEN Yuguang1 ZHANG Bin1 LI Lili2 YANG Yongsheng1 (1.College of Animal Science and Technology,Hunan Agricultural University,Changsha 410128,China;2.Laboratory of Animal Nutrition and Human Health,Key Laboratory of Agro-ecology,Institute of Subtropical Agriculture,The Chinese Academy of Sciences,Changsha 410125,China)
关键词:
adiponectin;adiponectin receptor(AdipoR);regulation mechanism of expression
摘  要:
Adiponectin is identified as protein factor secreted by adipose cell,via its receptors(AdipoRs) mediated regulation,plays important roles in physiological function,especially insulin-sensitizing,regulation of glucose and fat metabolism,endothelial cell protection and anti-inflammation in animals and human.Structure and distribution of AdipoR1 and AdipoR2,different factors and mechanisms affecting regulation of expression are reviewed in this paper.

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