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异亮氨酸对鱼类非特异性免疫功能影响的研究进展

作  者:
银龙;周小秋;赵娟;姜俊
单  位:
四川农业大学动物科技学院
关键词:
异亮氨酸;非特异性免疫;紧密连接;物理屏障;β防御素
摘  要:
异亮氨酸是鱼类的必需氨基酸,能增强鳃和肠道的物理屏障功能以及吞噬细胞的吞噬和杀菌能力,提高非特异性免疫因子的活性,促进抗炎因子表达,抑制促炎因子表达,发挥抗炎作用,进而增强非特异性免疫功能.本文就异亮氨酸对鱼类非特异性免疫功能的影响做一简要综述.
作  者:
YIN Long;ZHOU Xiaoqiu;ZHAO Juan;JIANG Jun;College of Animal Science and Technology,Sichuan Agricultural University;Institute of Animal Nutrition,Sichuan Agricultural University;
单  位:
YIN Long%ZHOU Xiaoqiu%ZHAO Juan%JIANG Jun%College of Animal Science and Technology,Sichuan Agricultural University%Institute of Animal Nutrition,Sichuan Agricultural University
关键词:
isoleucine;;non-specific immune;;tight junction;;physical barrier;;β-defensin
摘  要:
Isoleucine is an essential amino acid for fish,which can through enhancing the physical barrier function of gill and intestine,phagocytosis and bactericidal activity of phagocytes,increasing non-specific immune factor activities,promoting the expression of anti-inflammatory factors,inhibiting the expression of pro-inflammatory factors and playing an anti-inflammatory role to strengthen non-specific immune function. This article mainly aimed to reviewthe effects of isoleucine on non-specific immune function of fish.[Chinese Journal of Animal Nutrition,2019,31(7):3023-3030]

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