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Position: Home > Articles > Effect of Taurine on Blood Pressure and the Vasoactive Substance Concerning Hypertension in Rats Journal of Shenyang Agricultural University 2008,39 (3) 328-331

牛磺酸对大鼠血压及相关因子的影响

作  者:
胡建民;吕秋凤;杨建成;林树梅;杨群辉;金淑清;刘梅
单  位:
沈阳农业大学畜牧兽医学院
关键词:
牛磺酸;血压;大鼠;cAMP;cGMP
摘  要:
通过检测补充不同水平牛磺酸和-β丙氨酸(牛磺酸转运抑制剂)大鼠的血压和心肌中环一磷酸腺苷(Cyclic 3',5’-adenosine monophosphate,cAMP)、环一磷酸鸟苷(cyclic 3',5'-guanosine monophosphate,cGMP)和血清中Ca2+和Na+的含量,探讨牛磺酸对高血压发生的预防作用。试验结果表明:补充牛磺酸可使大鼠尾部动脉血压降低的同时,心肌中cGMP的含量提高44.2%(p<0.05),而对心肌中cAMP和血清Ca2+、Na+的含量变化均不显著(p>0.05)
译  名:
Effect of Taurine on Blood Pressure and the Vasoactive Substance Concerning Hypertension in Rats
作  者:
HU Jian-min,LU Qiu-feng,YANG Jian-cheng,LIN Shu-mei,YANG Qun-hui, JIN Shu-qing,LIU Mei (College of Animal Science and Veterinary Medicine,Shenyang Agricultural University,Shenyang 110161,China)
关键词:
taurine;blood pressure;rat;cAMP;cGMP
摘  要:
Different levels of taurine and β-alanine were added to deterrmine the blood pressure,the content of cAMP and cGMP in ardiac muscle,and the contents of Ca2+;Na+ in the serum.The results indicated that taurine reduced the tail arterial blood pressure,meanwhile increased the content of cGMP 44.2%(p<0.05),but no significant differences were found in the level of cAMP;Ca2+ and Na+(p>0.05).

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