中国农业科学院农业信息研究所 中国农学会
Agricultural Information Institute of CAAS China Association of Agricultural Science Societies
En
Ch
中国农业科学院农业信息研究所 中国农学会 主办

AI检索

订阅

返回顶部
当前位置: 首页 > 文章 > 藏灵菇源克鲁维酵母菌M3调节大鼠肠道菌群平衡的研究 食品科学 2016,37 (5) 197-201
Position: Home > Articles > Regulatory Effect of Kluyveromyces marxianus M3 Isolated from Tibetan Kefir on the Intestinal Flora Balance in Rats FOOD SCIENCE 2016,37 (5) 197-201

藏灵菇源克鲁维酵母菌M3调节大鼠肠道菌群平衡的研究

作  者：
董牧群;熊利霞;谢远红;张红星;刘慧;贾慧;连正兴
单  位：
中国农业大学动物科技学院;北京农学院食品科学与工程学院
关键词：
藏灵菇;马克斯克鲁维酵母菌;动物实验;肠道菌群平衡
摘  要：
利用从藏灵菇中筛选出的发酵性能优良且产胆盐水解酶的马克斯克鲁维酵母菌M3菌株,制备冻干菌粉作为受试物进行动物实验,探讨其对预防性高胆固醇血症大鼠肠道菌群平衡的作用。采用预防高胆固醇血症大鼠模型,将40只无特定病原体(specific pathogen free,SPF)级3周龄的大鼠分为高脂模型组、低剂量、中剂量和高剂量实验组进行实验。实验组分别灌胃低、中、高剂量的受试物,高脂模型组灌胃蒸馏水,连续7周。结果表明,前5周4组大鼠粪便中乳酸杆菌(lactobacilli)、沙门氏菌(Salmonella)、产气荚膜梭菌(Clostridium perfringens)的数量处于平缓变化状态,且3个实验组与高脂模型组相比无显著性差异;5周时,3个实验组大鼠粪便中乳杆菌的数量极显著高于高脂模型组(P<0.01),沙门氏菌的数量极显著低于高脂模型组(P<0.01),产气荚膜梭菌的数量显著低于高脂模型组(P<0.05);其中低剂量组的乳杆菌数量最高而沙门氏菌和产气荚膜梭菌数量最低,说明低剂量实验组优于中、高剂量实验组。显示藏灵菇源克鲁维酵母菌M3能够调节高胆固醇血症大鼠肠道有益菌的生长,并抑制有害菌的繁殖,具有良好的调节肠道菌群平衡的效果。
译  名：
Regulatory Effect of Kluyveromyces marxianus M3 Isolated from Tibetan Kefir on the Intestinal Flora Balance in Rats
作  者：
DONG Muqun;XIONG Lixia;XIE Yuanhong;ZHANG Hongxing;LIU Hui;JIA Hui;LIAN Zhengxing;Beijing Engineering Laboratory of Key Technology Development of Microecologics, Beijing Laboratory of Food Quality and Safety,College of Food Science and Engineering, Beijing University of Agriculture;College of Animal Science and Technology, China Agricultural University;
关键词：
Tibetan kefir;;Kluyveromyces marxianus;;animal experiment;;intestinal flora balance
摘  要：
To evaluate the effects of Kluyveromyces marxianus M3, with good fermentation performance and high ability to produce bile salt hydrolase, isolated from Tibetan kefir on the intestinal flora balance in experimental hypercholesterolemic rats, 40 rats(43 weeks old) were divided into 4 groups and fed a high fat diet supplemented with low, medium and high dose of freeze-dried K. marxianus M3 powder for a 7-week experimental period. According to our results, in the first five weeks, the numbers of 3 kinds of bacteria in rat feces gradually changed, and there was no significant difference between the three experimental groups and the high-fat model group; at the fifth week, the preventive hypercholesterolemia model was established successfully, the number of Lactobacillus in the three experimental groups was significantly higher than that in the high-fat model group(P < 0.01), while the number of Salmonella(P < 0.01) and Clostridium perfringens(P < 0.05) was significantly lower than in the high-fat model; among all experimental groups, the number of Lactobacillus in the low dose group was the highest while Salmonella and Clostridium perfringens were the lowest, showing that the effect of low dose was better than the medium and high doses. These results demonstrated that K. marxianus M3 could promote the growth of intestinal beneficial bacteria and inhibit the breeding of harmful bacteria in the hypercholesterolemic rats, having a good effect on the intestinal flora balance.

相似文章

导出引用
计量
文章访问数: 6
HTML全文浏览量: 0
PDF下载量: 0

所属期刊

推荐期刊

友情链接Friendly link
农业信息研究所Agricultural information institute 农业智能知识服务平台Agricultural intelligent knowledge service platform 农业学术服务平台Agricultural Knowledge Service System 中国知网CNKI 维普网VIP 万方WANFANG DATA
联系我们Contact us

电话Tell：010-82109652-808

邮箱E-mail：agrijournal@caas.cn

服务Service
关于我们About us 意见建议Opinions and suggest
版权说明Copyright
单位：中国农业科学院农业信息研究所 中国农学会 © 2017中国农业科学院农业信息研究所 ICP备案号：京ICP备09089781号-46