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Position: Home > Articles > Study on the Influence of Hibiscus Sabdariffa Polysaccharide on Humoral Immunity and Cellular Immunity Function in Mice Journal of Liaoning Agricultural Technical College 2015 (1) 1-2

玫瑰茄多糖对小鼠体液免疫和细胞免疫功能的影响

作  者:
张赛男
单  位:
赣南医学院药学院
关键词:
玫瑰茄;多糖;体液免疫;细胞免疫
摘  要:
玫瑰茄多糖设置低、中、高3个剂量组和1个对照组,给(SPF)小鼠连续灌胃4周,以脾淋巴细胞转化功能、迟发性变态反应(DTH)、溶血空斑数、半数溶血值(HC50)等为指标,观察瑰茄多糖对小鼠体液免疫和细胞免疫功能的影响。结果表明:与对照组比较,脾淋巴细胞转化功能、迟发性变态反应(DTH)、溶血空斑数、半数溶血值(HC50)测定实验均有显著提高作用。其中,高剂量组对小鼠迟发型变态反应能力(DTH)影响、半数溶血值(HC50)达到极显著水平(P<0.01),高剂量组对小鼠溶血空斑数的影响达到显著水平(P<0.05)。说明玫瑰茄多糖具有增强小鼠体液免疫功能和细胞免疫功能的作用。
译  名:
Study on the Influence of Hibiscus Sabdariffa Polysaccharide on Humoral Immunity and Cellular Immunity Function in Mice
作  者:
ZHANG Sainan;College of Pharmacy,Gannan Medical University;
关键词:
Hibiscus Sabdariffa;;Polysaccharide;;humoral immunity;;cellular immunity
摘  要:
( SPF) Rats were feed with low、 medium、 high dose of Hibiscus Sabdariffa polysaccharide and 1 control group for4 weeks to observe the humoral immunity and cellular immunity function of Hibiscus Sabdariffa polysaccharides by measurement spleen lymphocyte transform function、 delayed type hypersensitivity( DTH) 、 the serum hemolysin concentration、 the serum hemolysin concentration( HC50). Results, To compared with control group, spleen lymphocyte transform function、 delayed type hypersensitivity( DTH) 、 the serum hemolysin concentration、 the serum hemolysin concentration( HC50) were obviously improved. And the influence of high dose group on delayed type hypersensitivity( DTH) 、 the serum hemolysin concentration( HC50) reached extremely significant level(P<0.01), the influence of high dose group on the serum hemolysin concentration reached significant level( P<0.05).Conclusions,Hibiscus Sabdariffa polysaccharide has the role of enhancing humoral immunity and cellular immunity function in mice.

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