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当前位置: 首页 > 文章 > 新疆地区汉族、维吾尔族和哈萨克族脂代谢异常检出率分析 石河子大学学报(自然科学版) 2016,34 (1) 63-68
Position: Home > Articles > Analysis of the detection rate of dyslipidemia in Han,Uygur and Kazak population in Xinjiang Area Journal of Shihezi University(Natural Science) 2016,34 (1) 63-68

新疆地区汉族、维吾尔族和哈萨克族脂代谢异常检出率分析

作  者：
哈晓丹;王翠喆;李伟;许彭;王婷婷;王燕;张君
单  位：
新疆维吾尔自治区人民医院内分泌科;石河子大学医学院医学遗传学教研室
关键词：
汉族;维吾尔族;哈萨克族;脂代谢异常
摘  要：
为了解新疆地区汉族、维吾尔族和哈萨克族脂代谢特征,阐明代谢综合征各指标间的相互关系,以2014年6~12月新疆维吾尔自治区人民医院门诊体检个体为研究对象,包括年龄在20~90岁之间的汉族1359名、维吾尔族172名、哈萨克族630名,收集其一般资料,检测空腹血糖、血浆总胆固醇、三酰甘油、高密度脂蛋白胆固醇及低密度脂蛋白胆固醇等指标,并对不同民族血脂异常检出率进行分析比较。结果显示,维吾尔族体重、腰围、臀围、腰臀比、体质指数、肥胖及腹型肥胖检出率、血压,以及各项血脂指标均显著高于汉族及哈萨克族。新疆地区汉族、维吾尔族和哈萨克族体检人群血脂异常总检出率为23.23%,男性(32.40%)显著高于女性(17.61%)(P<0.001);高胆固醇血症检出率、高三酰甘油血症检出率以及低密度脂蛋白胆固醇血症检出率维吾尔族显著高于汉族和哈萨克族(P<0.001);各项血脂指标中除高密度脂蛋白胆固醇与体重、体质指数、腰围、臀围、腰臀比、收缩压、舒张压、空腹血糖、2 h后血糖、空腹胰岛素以及2 h后胰岛素等指标在汉族和哈萨克族人群中显著负相关,其余指标均与上述资料显著正相关(P<0.01)。而在维吾尔族人群中仅有总胆固醇与身高、臀围、舒张压显著正相关,低密度脂蛋白与2 h血糖显著正相关(P<0.01),其余指标之间均无显著相关性。结果表明,血脂异常的发生在民族及性别间存在显著差异,维吾尔族更易发生脂代谢紊乱,可能与其独特的遗传背景有关。
译  名：
Analysis of the detection rate of dyslipidemia in Han,Uygur and Kazak population in Xinjiang Area
作  者：
HA Xiaodan;WANG Cuizhe;LI Wei;XU Peng;WANG Tingting;WANG Yan;ZHANG Jun;Department of Genetics, School of Medicine, Shihezi University;Clincal Laboratory, The First Affiliated Hospital, School of Medicine, Shihezi University;Endocrinology Department, Xinjiang Uygur Autonomous Region People's Hospital;
关键词：
Han population;;Uygur population;;Kazak population;;dyslipidemia
摘  要：
To observe the lipid metabolism characteristics and clarify the relationship between the metabolic syndrome indicators in Han, Uygur and Kazak population in Xinjiang area. Physical examination people at outpatient department of People's hospital of Xinjiang Uygur Autonomous Region were selected, in which Han 1359, Uygur 172, Kazak 630 residents aged between 20 to90 years were enrolled in this study. Their general information and serum total cholesterol(TC), triglyceride(TG), high-density lipid-cholesterol(HDL-C), and low-density lipid cholesterol(LDL-C) were tested. And according to the judgment standard of dyslipidemia detection rate for comparative analysis. Results showed that the body weight, waist circumference, hip circumference, waist hip ratio, body mass index, obesity and abdominal obesity detection rate, blood pressure, and blood lipids index were significantly higher in Uygur people than that in the Han and Kazak people. The detection rate of dyslipidemia was23.23%(32.40% for men,17.61% for women, respectively). It was significantly higher in men than in women(P<0.001).The detection rate of high TC level, high TG level and low HDL-C level were significantly higher in Uygur people than Han people and Kazak people(P<0.001). In addition to HDL-C in blood lipids index was significantly negative correlated with weight, body mass index, waist circumference, hip circumference, waist hip ratio, systolic pressure, diastolic blood pressure,fasting plasma glucose,2 hour plasma glucose, fasting insulin, 2 hour insulin and other blood lipids index were significantly positive correlated with above indicators in Han and Kazak population(P<0.001).And in Uygur population, TC is significantly positive correlated with height, hip circumference and diastolic blood pressure, LDL is significantly positive correlated with 2hour plasma glucose(P <0.01). And the rest had no significant correlation among indicators. In summary, there are significant differences between ethnic and gender on dyslipidemia, and the Uygurs are more likely to produce lipid metabolic disorders,which may be related to its unique genetic background.

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