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HPLC法测定泥土中氯硝柳胺的含量

作  者:
严相平;王康蕊;王浦海;戴建荣
单  位:
江苏省血吸虫病防治研究所;南京工业大学江苏省药物研究所
关键词:
氯硝柳胺;高效液相色谱法;含量测定
摘  要:
[目的]建立测定泥土中氯硝柳胺含量的HPLC分析方法。[方法]以C18柱,流动相为甲醇-20 mol/L磷酸二氢钾溶液(含磷酸0.1%)(体积比85∶15),检测波长为236 nm。[结果]方法的线性相关系数为0.999 9,相对标准偏差0.8%,平均回收率为97.54%。[结论]该方法准确,可用以测定泥土中氯硝柳胺含量。
译  名:
Determination of Nclosamide in Soil by HPLC
作  者:
YAN Xiang-ping1,WANG Kang-rui1,WANG Pu-hai1,DAI Jian-rong2(1.Jiangsu Provincial Institute of Materia Medica,Nanjing University of Technology,Nanjing 210018,China;2.Jiangsu Institute of Parasitic Diseases,Wuxi 214064,Jiangsu,China)
关键词:
niclosamide;HPLC;determination
摘  要:
To establish a HPLC method for the determination of niclosamide in soil.[Methods]C18column wasused with the mobile phase of methanol-20 mol/L KH2PO4(including 0.1%phosphoric acid)(85:15,by vol).The detectivewavelength was 236 nm.[Resuts]The liner correlation coefficient was 0.9999,the RSD was 0.8%,average recovery was97.54%.[Conclusions] The method was accurate and could be applied for the determination of niclosamide in soil.

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