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ACEI发酵乳的稳定性与降血压效果试验研究

作  者:
马海乐;吴琼英
单  位:
江苏科技大学生物技术学院;江苏大学生物与环境工程学院
关键词:
发酵乳;稳定性;降血压效果;原发性高血压大鼠
摘  要:
对具有抑制血管紧张素转换酶活性的发酵乳(ACEI发酵乳)的热稳定性、耐碱性和抗肠道酶解能力进行研究,结果表明:ACEI发酵乳具有良好的耐高温性能;在20℃,pH≤11.0的情况下,发酵乳对ACE的抑制活性基本保持稳定;ACEI发酵乳具有抗肠道酶解能力。以10ml/kgbw发酵乳一次性灌胃原发性高血压大鼠,大鼠动脉血压变化最大值为:-29±14.75mmHg,证实所制得的发酵乳具有明显的降血压效果。
译  名:
Study on Stabilities and Antihypertensive Effect of ACEI Fermented Milk
作  者:
MA Hai-le1, WU Qiong-ying2 (1.College of Biology and Environment Engineering, Jiangsu University, Zhenjiang 212013,China; 2.Biotechnology College, Jiangsu University of Science and Technology, Zhenjiang 212018,China)
关键词:
fermented milk;stabilities;antihypertensive effect;spontaneously hypertensive rats
摘  要:
To study on stabilities of heat, pH and intestinal enzymes proteolysis, the results indicated that: the fermented milk could inhibit the activity of angiotensinⅠ-converting enzyme in good capability to endure high temperature. The activity to incubation ACE was kept in conditions of 20℃ and pH≤11.0, so the fermented milk could have the ability to resist intestinal enzymes proteolysis. The spontaneously Hypertensive Rats were each given 10ml/kg bw fermented milk by single gastric intubation. The systolic blood pressure of rats was decreased significantly: -29±14.75mmHg. This result testified that the fermented milk had apparent effect on depressing blood pressure.

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