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Position: Home > Articles > Study on Inhibition of in vitro Growth of Enteropathogens of Weanling Pigs Intestinal by Bifidobacterium bifidum and its Mechanisms Chinese Journal of Animal and Veterinary Sciences 2004,35 (6) 664-669

两歧双歧杆菌体外抑制断奶仔猪肠道病原菌的研究及其机理探讨

作  者:
郭彤;许梓荣
单  位:
上海水产大学生命科学与技术学院;浙江大学动物分子营养学教育部重点实验室浙江大学饲料科学研究所
关键词:
两歧双歧杆菌;断奶仔猪;肠道病原菌;生长抑制;细菌共凝集
摘  要:
为探明两歧双歧杆菌对仔猪肠道病原菌的抑菌机理,通过两歧双歧杆菌与大肠杆菌K88、猪霍乱沙门氏菌和鼠伤寒沙门氏菌分别进行6、12、24、48h共培养,判断抑菌效果并研究其抑菌机理。结果表明,两歧双歧杆菌在体外对仔猪肠道3种病原菌的生长均有显著的抑制作用,而病原菌并不影响两歧双歧杆菌的生长。通过原子力显微镜照片可见,两歧双歧杆菌不能与致病菌大肠杆菌K88、猪霍乱沙门氏菌和鼠伤寒沙门氏菌发生共凝集现象。
译  名:
Study on Inhibition of in vitro Growth of Enteropathogens of Weanling Pigs Intestinal by Bifidobacterium bifidum and its Mechanisms
作  者:
GUO Tong~(1,2), XU Zi-rong~2(1.College of Auqa-life Science and Technology, Shanghai Fisheries University, Shanghai 200090, China;Feed Science Institute of Zhejiang University, Hangzhou 310029, China)
关键词:
Bifidobacterium bifidum; weanling pigs; enteropathogens; growth inhibition; coaggregation
摘  要:
Bifidobacterium bifidum was incubated simultaneously with enteropathogen Escherichia coli K_(88),S. cholerasuis and S. typhimurium. After 6,12,24 and 48 h, bacterial counts of the pathogens and of the B. bifidum were performed. The results showed that B. bifidum in vitro inhibited the growth of Escherichia coli K_(88),S. cholerasuis and S. typhimurium under these conditions. In contrast, the presence of the enteropathogens did not affect the growth of the B.bifidum. But B. bifidum did not showed coaggregation ability with three enteropathogens by atom force microscope(AFM).

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