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Position: Home > Articles > Effect of Carnosic Acid on Free Radical-mediated Oxidative Damage to Proteins FOOD SCIENCE 2013,34 (15) 281-284

鼠尾草酸对自由基诱导蛋白质氧化损伤的保护作用

作  者:
相启森;孟旭;乔燕;胥莉;刘学波
单  位:
西北农林科技大学食品科学与工程学院
关键词:
鼠尾草酸;自由基;蛋白质;羰基化
摘  要:
评价鼠尾草酸对自由基诱导蛋白质氧化损伤的保护作用。采用Cu2+/H2O2诱导牛血清白蛋白(BSA)和SD大鼠肝匀浆蛋白氧化损伤反应体系,通过考马斯亮蓝R-250染色法和免疫印迹法检测蛋白质氧化降解和羰基化程度。结果表明:鼠尾草酸能够抑制Cu2+/H2O2诱导BSA和SD大鼠肝匀浆蛋白的氧化降解和羰基化损伤。
译  名:
Effect of Carnosic Acid on Free Radical-mediated Oxidative Damage to Proteins
作  者:
XIANG Qi-sen,MENG Xu,QIAO Yan,XU Li,LIU Xue-bo*(College of Food Science and Engineering,Northwest A&F University,Yangling 712100,China)
关键词:
carnosic acid;free radical;protein;carbonylation
摘  要:
The effect of carnosic acid(CA) on free radical-induced protein oxidative degradation and carbonylation was explored in the present study.Cu2+/H2O2 reaction system was used to induce the oxidation of bovine serum albumin(BSA) and proteins in liver homogenate from SD rats.The results showed that CA significantly inhibited oxidative degradation and carbonylation of BSA and proteins in liver homogenate.This investigation provides preliminary evidence that CA has the potential to be used in functional foods.

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