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β-羟基-β-甲基丁酸在猪生产中的应用及其作用机制

作  者:
万海峰;孙鹏;黄琼;吴高岭;钟铭;伍剑;左晓灵;吴德
单  位:
咸宁职业技术学院;广西商大科技股份有限公司;四川农业大学动物营养研究所
关键词:
β-羟基-β-甲基丁酸;肌纤维发育;母猪;仔猪;作用机制
摘  要:
β-羟基-β-甲基丁酸(HMB)是亮氨酸的一种代谢产物.研究发现,HMB通过母体调节仔猪肌纤维的生长发育,改善了仔猪生长性能及上市期肉品质.同时,HMB通过提高母猪初乳脂肪及免疫球蛋白含量改善哺乳仔猪成活率.而且HMB有利于促进仔猪断奶后生长,缓解断奶应激.HMB影响母仔猪生产性能的机制是通过促进仔猪胎儿期肌纤维生肌作用、新生期肌纤维类型转换,以及促进仔猪骨骼肌蛋白合成,并在断奶应激下抑制肌肉蛋白质分解途径等来实现.
译  名:
Application of β-Hydroxy-β-Methylbutyrate in Pig Production and Its Mechanism
作  者:
WAN Haifeng;SUN Peng;HUANG Qiong;WU Gaoling;ZHONG Ming;WU Jian;ZUO Xiaoling;WU De;Xianning Vocational Technical College;South Hubei Industrial Technology Research Institute for Characteristic Agriculture;Guangxi Shangda Technology Co., Ltd.;Guangxi Breeding Pigs Nutrition Research Center of Engineering Technology;Institute of Animal Nutrition, Sichuan Agricultural University;
关键词:
β-hydroxy-β-methylbutyrate(HMB);;muscle fiber development;;sow;;piglet;;mechanism
摘  要:
β-hydroxy-β-methylbutyrate(HMB) is a metabolite of leucine. Studies have found that dietary supplementation of HMB for sows during gestation and lactation has a positive effect in muscle fiber development and growth of piglets before and after birth, which improves growth performance and meat quality of pigs at market. At the same time, the colostrum fat and immune globulin content have been added by feeding HMB to sows during the perinatal stage, which increases the survival rate of piglets. In addition, feeding HMB to piglets during post weaning also could improve the growth performance and reduce the weaning stress. There are some possible mechanisms for dietary HMB supplementation to improve production performance of sows or piglets as following, including promoting the myogenesis and the type conversion of muscle fiber, and enhancing the synthesis of skeletal muscle protein, and inhibiting the protein decomposition pathway under weanling stress for piglets.

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