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Position: Home > Articles > Novel Process of Condensation for Preparation of Flumorph Modern Agrochemicals 2009,8 (2) 37-38

氟吗啉缩合新工艺的研究

作  者:
孙德群;田爱俊;杨越
单  位:
威海秀水药物研发有限公司;山东大学威海分校海洋学院
关键词:
工艺;氟吗啉;氨基钠
摘  要:
在甲苯溶剂中,回流状态下,以氨基钠为碱催化缩合生成氟吗啉,所得产品含量用高效液相色谱定量分析高于95%,收率达80%。该方法未见国内外文献报道,具有高效、低成本、对环境友好的优点。
译  名:
Novel Process of Condensation for Preparation of Flumorph
作  者:
SUN De-qun1,TIAN Ai-jun2,YANG Yue2(1.Marine College,Shandong University at Weihai,Shandong Weihai 264209,China;2.Weihai Xiushui Pharmaceutical R & D Company,Shandong Weihai 264209,China)
关键词:
process;flumorph;sodium amide
摘  要:
Flumorph was prepared in a novel process,in which the sodium amide was employed as base and the toluene was used as solvent.The content and yield of the flumorph were reached over 95% and 80% respectively.This process has the advantage of low cast,effective produce and environment friendly while comparing with other related methods.

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