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L-肉碱的生理功能、生物学制备及检测方法研究进展

作  者:
杨月英;黄娇芳;顾金杰;史吉平;王红英
单  位:
生物炼制实验室;生物灵感工程实验室;中国科学院上海高等研究院;上海科技大学物质科学与技术学院;大连工业大学生物工程学院
关键词:
L-肉碱;脂肪酸代谢;生物合成法;活性异构体;检测
摘  要:
L-肉碱即左旋肉碱,又叫维生素BT,是一种广泛存在于动物、植物以及部分微生物体内的活性异构体,其主要功能是参与脂肪酸的代谢。近年来,L-肉碱越来越广泛地用于新型的功能食品和降血脂新药的开发,因此,其生产方法和检测都面临更高的技术要求。文章重点综述了L-肉碱的生理功能、生物法制备以及检测方法,并对其未来发展方向进行展望。
译  名:
Advances in Physiological Functions,Biotransformation and Detection of L-Carnitine
作  者:
YANG Yueying;HUANG Jiaofang;GU Jinjie;SHI Jiping;WANG Hongying;College of Biological Engineering,Dalian Polytechnic University;Laboratory of Biorefinery,Shanghai Advanced Research Institute,Chinese Academy of Sciences;Integrative Bio-inspired Molecular Engineering Laboratory,School of Physical Science and Technology,Shanghai Tech University;
关键词:
L-carnitine;;fatty acid metabolism;;biotransformation;;active isomer;;detection
摘  要:
L-Carnitine,also named vitamin BT,is an active compound found in animals and vegetal tissues,as well as in micr oorganisms.L-carnitine plays an important role in fatty acid metabolism.In recent years,L-carnitine has been increasingly used as a novel food additive and clinically applied in reducing blood fat,so that the demand for L-carnitine is increasing in the worldwide market,and the development of manufacturing and detection methods is needed.Herein,the physiological functions,biotransformation and detection methods of L-carnitine are summarized,and the future directions of L-carnitine are put forward in this review.

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