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Position: Home > Articles > Study on Extraction of Pu'er Tea Polysaccharides and Hypoglycemic Chinese Agricultural Science Bulletin 2009,25 (15) 55-59

普洱茶多糖的提取及降血糖的研究

作  者:
周斌星;孔令波;陈军贤
单  位:
云南农业大学普洱茶学院
关键词:
普洱茶;茶多糖;糖尿病小鼠;血糖值
摘  要:
从云南大叶种晒青毛茶经潮水渥堆做成的普洱茶中,提取茶叶多糖,通过分离、纯化得到纯品茶多糖(TPS),配制成不同浓度的茶多糖溶液,以研究测定其对小鼠降血糖效果的差异;在动物活体试验中共设4组:正常对照组、模型对照组、低剂量注射组、高剂量注射组。采用腹腔注射,正常对照组和模型对照组注入同等体积的蒸馏水。糖尿病试验小鼠选择经四氧嘧啶诱发造模后合格的小鼠,观测其体重与血糖的变化情况,为期一周。试验结果表明:(1)普洱茶多糖具有促进糖尿病小鼠体重恢复的作用,但无显著性差异。(2)普洱茶多糖能有效的降低糖尿病小鼠的血糖值,高剂量的普洱茶多糖(160mg/kg)比低剂量的普洱茶多糖(80mg/kg)降血糖效果要好,在统计上降血糖幅度差异性显著(P<0.05),并且呈现一定剂量-反应关系。
译  名:
Study on Extraction of Pu'er Tea Polysaccharides and Hypoglycemic
作  者:
Zhou Binxing, Kong Lingbo, Chen Junxian (College of Pu'er Tea, Yunnan Agricultural University, Kunming 650201)
关键词:
Pu'er tea, tea polysaccharides, diabetic mice, blood sugar level
摘  要:
In this experiment, extract polysaccharides from pu'er tea. The pu'er tea polysaccharide make through the separation and purification, then prepare of different concentrations of tea polysaccharide solution. In vivo tests in animals for four groups of Communist China: normal control group, diabetes mellitus (DM) model for the control group, diabetes 80 mg/(kg·d) dose injection group, diabetes 160 mg/(kg·d) dose injection group, Normal control group and model control group injected the same volume of distilled water and used the intraperitoneal injection. Choice test in mice diabetic by alloxan-induced model in mice after the qualified, Observated their body weight and blood glucose changes during one week. The results showed that: (1)The pu'er tea polysaccharide have the resumption of the promotion of the polysaccharide tea weight of diabetic mice,however, no significant difference.(2)The pu'er tea polysaccharide could effectively lower blood glucose levels in diabetic mice, The high doses of tea polysaccharide (160 mg/kg) relate hypoglycemic effect better than low doses of tea polysaccharide (80 mg/kg). The hypoglycemic rate was significantly higher in statistics(P<0.05), and have a dose - response relationship.

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