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Position: Home > Articles > Study on Protection of Proanthocyaidins from Lotus Seedpod (LSPC) on Subchronic Damage Caused by ~(60)Co-γ Radiaton FOOD SCIENCE 2006,27 (1) 220-222

莲房原花青素对~(60)Co-γ射线致免疫器官损伤的防护作用

作  者:
段玉清;张海晖;唐瑛;吴佳;谢笔钧
单  位:
江苏大学生物与环境学院;江苏大学生物与环境学院,华中农业大学食品科技学院 湖北武汉430070,江苏大学生物与环境学院,广州军区武汉总医院,华中农业大学食品科技学院,华中农业大学食品科技学院,,江苏镇江212013,江苏镇江212013,湖北武汉430070,湖北武汉430070,湖北武汉430070
关键词:
莲房;原花青素;抗辐射;脏器
摘  要:
目的:研究莲房原花青素(LSPC)对60Co-γ射线致小鼠脏器损伤的影响。方法:给小鼠连续灌胃不同剂量的LSPC15d后,接受剂量4.0Gy60Co-γ射线照射后,于第3d处死小鼠,测定脏器增长指数并进行形态学观察。结果:小鼠经4.0Gy60Co-γ一次全身辐照后,100、200mg/kgbwLSPC组能使小鼠脾脏和胸腺增长指数明显提高,且与辐射对照组间有显著性差异(分别为p<0.01和p<0.05)。LSPC可不同程度的保护或恢复60Co-γ射线致小鼠的脾脏、胸腺的损伤。结论:LSPC对4.0Gy60Co-γ射线亚慢性辐射致免疫器官损伤有一定的保护作用。
译  名:
Study on Protection of Proanthocyaidins from Lotus Seedpod (LSPC) on Subchronic Damage Caused by ~(60)Co-γ Radiaton
作  者:
DUAN Yu-qing1,2,ZHANG Hai-hui1,TANG Ying3,WU Jia2,XIE Bi-jun2 (1.School of Biological and Environmental Engineering, Jiangsu University, Zhenjiang 212013, China; 2.College of Food Science and Technology, Huazhong Agricultural University, Wuhan 430070, China; 3.Wuhan Chief Hospital, Guangzhou Military Area, Wuhan 430070, China)
关键词:
lotus seedpod;proanthocyanidins;antiradiation;viscera
摘  要:
Objective:Investigation on protection effects of proanthocyanidins from Lotus Seedpod (LSPC) on mice viscera damage caused by 60Co-γ radiation. Methods:Mice were given different dosages of LSPC continuously for 15 days by gavage, then exposed to 4.0 Gy 60Co-γ radiation, the mice were killed after 3 days exposure and assayed for viscera increase index with additional morphology observation. Results:After mice were exposed to 4.0 Gy 60Co-γ, the increase index of mice spleen and thymus were up to 100, 200mg/kg bw respectively, and showed significiant difference to the control group (p<0.01 and p< 0.05 respectively). LSPC can protect or restore mice spleen and thymus damages caused by 60Co-γ. Conclusions: LSPC had a certain of protective effect on subchronic damages to viscera by 4.0 Gy 60Co-γ.

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