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当前位置: 首页 > 文章 > 甘草次酸对早期断奶仔猪内脏器官发育的影响 畜牧兽医学报 2008,39 (7) 989-993
Position: Home > Articles > Effect of Glycyrrhetinic Acid on Viscera Development in Early-weaned Piglet Chinese Journal of Animal and Veterinary Sciences 2008,39 (7) 989-993

甘草次酸对早期断奶仔猪内脏器官发育的影响

作  者：
何子双;胡元亮;印遇龙;黄瑞林;李飞务;王贵平
单  位：
中国科学院亚热带农业生态研究所;南京农业大学动物医学院;广东省农业科学院兽医研究所
关键词：
甘草次酸;仔猪;内脏指数;形态学;鸟氨酸脱羧酶
摘  要：
7日龄断奶长×大仔公猪,以代乳粉配制代乳液饲养。12头仔猪9日龄按体重随机均分为对照组(基础日粮)和甘草次酸(GA)组(代乳粉添加200 mg/kg的GA),每组6头。连续饲喂12 d。仔猪21日龄称重后处死,测定内脏指数、小肠黏膜上皮细胞蛋白质含量、空肠和回肠黏膜绒毛高度、隐窝深度和固有层厚度以及空肠上皮细胞鸟氨酸脱羧酶活性。结果表明,与对照组相比,GA组肝脏指数、小肠质量/长度比、空肠和回肠绒毛高度及回肠隐窝深度显著增加(P<0.05),空肠上皮细胞鸟氨酸脱羧酶活性显著增强(P<0.01)。提示GA促进了仔猪小肠和肝脏的发育,改善黏膜结构;提高上皮细胞鸟氨酸脱羧酶活性可能是GA影响小肠发育的分子机制之一。
译  名：
Effect of Glycyrrhetinic Acid on Viscera Development in Early-weaned Piglet
作  者：
HE Zi-shuang1,3,HU Yuan-liang1,YIN Yu-long2,HUANG Rui-lin2,LI Fei-wu2,WANG Gui-ping3(1.College of Veterinary Medicine,Nanjing Agricultural University,Nanjing 210095,China;2.Institute of Subtropical Agriculture,Chinese Academy of Sciences,Changsha 410125,China;3.Veterinary Medicine Institute of Guangdong Academy of Agricultural Sciences,Guangzhou 510640,China)
关键词：
glycyrrhetinic acid;piglet;viscera index;morphology;ornithine decarboxylase
摘  要：
Landrace Yorkshire male pigs were weaned at 7-day old and fed with milk prepared by milk-replacing powder(MRP) and water.At 9-day old,twelve pigs were randomly assigned into control(basic diet) or glycyrrhetinic acid(GA) group(MRP containing 200 mg/kg GA) according to body weight,6 pigs each.The pigs were fed with corresponding feed for 12 days.Pigs were weighed and killed at 21-day old,and the viscera index,the protein content in enterocytes of small intestine and the ornithine decarboxylase(ODC) activity in that of jejunum,and the villus height,crypt and lamina propria depth of jejunum and ileum were determined.The results showed that,compared with the control,the liver index and small intestine mass/length,the villus height of jejunum and ileum and the crypt of ileum in GA group were increased(P<0.05);The ODC activity was enhanced(P<0.01).It is indicated that the development of liver and small intestine of piglet were boosted and the mucosa structure was improved by GA;And increasing ODC activity is one of the potentially molecular mechanism of GA on the small intestine.

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