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Position: Home > Articles > Expression of β-catenin in the Skin of Liaoning Cashmere Goats Journal of Economic Animal 2012,16 (3) 144-147

β-catenin基因在辽宁绒山羊皮肤毛囊中表达的研究

作  者:
谷博;孙丽敏;姜怀志
单  位:
吉林农业大学动物科学技术学院
关键词:
β-catenin;毛囊;发育;辽宁绒山羊
摘  要:
β-catenin是Wnt信号途径中的重要调控因子,对毛囊细胞的生长、分化、运动、凋亡的调节都具有重要的作用。采用荧光定量PCR方法检测45日龄、365日龄、730日龄的辽宁绒山羊皮肤中β-catenin mRNA的表达,分析其在不同日龄辽宁绒山羊皮肤上的表达差异。结果表明:β-连环蛋白在不同年龄辽宁绒山羊皮肤中均有表达。45日龄的β-catenin基因mRNA表达量极显著(P<0.01)地高于365日龄(1周岁)和730日龄(2周岁)的表达量,而365日龄(周岁)与730日龄(2周岁)间β-catenin基因mRNA表达量则差异不显著(P>0.05)。说明β-catenin在绒山羊皮肤毛囊的发育和成熟过程中发挥重要作用。
译  名:
Expression of β-catenin in the Skin of Liaoning Cashmere Goats
作  者:
GU Bo,SUN Li-min,JIANG Huai-zhi(College of Animal Science and Technology,Jilin Agricultural University,Changchun 130118,China)
关键词:
β-catenin;hair follicle;development;Liaoning cashmere goats
摘  要:
β-catenin is an important regulatory factor in Wnt signal pathway,and plays an important role in growth and development,organizational function of organisms of follicle cell.In order to study the expression of β-catenin in the skin of Liaoning cashmere goat at the ages of 45 days,365 days,730 days old,Real-time PCR technology was used in the experiment.The results showed that β-catenin could be expressed in the skin of Liaoning cashmere goats at the different ages.The expression amount of β-catenins were significant higher at the age 45 days old than that at the age of 365 days old and 730 days old(P<0.01),however,the expression amount of β-catenin were similar between 365 days old and 730 days old.This experiment showed that β-catenin played an important role in growth and maturation processes of skin hair follicle of cashmere goat.

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